Motor proteins. 1: kinesins.
Motor proteins. 1: kinesins.
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发表时间：
1994
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通讯作者：
Bloom Gs;S. Endow
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作者：
Bloom Gs;S. Endow
关于驱动蛋白的进展现在正以快速且加速的速度取得。驱动蛋白本身的体内功能、生物物理和酶学特性正在以越来越详细的水平进行探索。驱动蛋白相关的蛋白质现在有几十个，尽管对大多数蛋白质的一级结构的了解多于其功能，但这种趋势已经发生逆转。例如，关于驱动蛋白相关蛋白 ncd 的知识正在迅速扩展，并且对其三维结构的了解比对驱动蛋白重链的了解更多。本书全面回顾了已发表的关于驱动蛋白和驱动蛋白相关蛋白的主要著作。希望这篇手稿能够补充其他最近的评论文章 [17, 20, 25, 37, 60-62, 67, 69, 75, 85-88, 231, 233, 238, 244, 269-271, 281, 282, 292] 或专注于更多内容的书籍 [49, 227, 293]驱动蛋白家族的选择性方面，或者更普遍地针对 MT 运动蛋白。根据蛋白质概况系列的既定目的，计划至少在未来几年内对驱动蛋白进行年度更新审查。
Progress regarding the kinesins is now being made at a rapid and accelerating rate. The in vivo-functions, and biophysical and enzymatic properties of kinesin itself are being explored at ever increasing levels of detail. The kinesin-related proteins now number several dozen, and although more is known about primary structure than function for most of the proteins, this trend is already reversing. For example, knowledge about the kinesin-related protein, ncd, is expanding rapidly, and more is already known about its three-dimensional structure than is known for kinesin heavy chain. This volume presents a comprehensive review of the major published works on kinesin and kinesin-related proteins. Hopefully, this manuscript will complement other recent review articles [17, 20, 25, 37, 60-62, 67, 69, 75, 85-88, 231, 233, 238, 244, 269-271, 281, 282, 292] or books [49, 227, 293] that have focused on more selective aspects of the kinesin family, or have been aimed more generally at MT motor proteins. In line with the stated purpose of the Protein Profile series, annual updates of the review on the kinesins are planned for at least the next few years.