Effect of oral sucrose on blood pressure in the spontaneously hypertensive rat.
Effect of oral sucrose on blood pressure in the spontaneously hypertensive rat.
复制标题
口服蔗糖对自发性高血压大鼠血压的影响。
DOI：
10.1016/0026-0495(81)90173-6
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Landsberg,L
中科院分区：
文献类型：
--
作者：
Young,JB;Landsberg,L
在自发性高血压大鼠(SHR)中，增加碳水化合物摄入量而不改变钠摄入量与血压升高有关。饲喂蔗糖饲料一周后，三组自发性高血压大鼠的血压平均升高14毫米汞柱(9%)，但对同品系正常血压大鼠(Wistar-京都-WKY)的血压没有影响。补充脂肪(等卡路里到蔗糖)对SHR的血压没有影响。这些数据与饮食诱导的交感活动增加可能会提高易感动物的血压的假设是一致的。
In the spontaneously hypertensive rat (SHR) increased carbohydrate intake without alteration in sodium intake is associated with elevated blood pressure. One week of feeding sucrose-supplemented chow increased blood pressure an average of 14mm Hg (9%) in three separate groups of SHR, but did not affect blood pressure in normotensive rats of the same strain (Wistar-Kyoto-WKY). Fat supplementation (isocaloric to sucrose) was without effect on blood pressure in SHR. These data are consistent with the hypothesis that diet-induced increases in sympathetic activity may elevate blood pressure in susceptible animals.