CARDIAC-ARRHYTHMIA AND CONDUCTION DISTURBANCES DURING SLEEP IN 400 PATIENTS WITH SLEEP-APNEA SYNDROME
CARDIAC-ARRHYTHMIA AND CONDUCTION DISTURBANCES DURING SLEEP IN 400 PATIENTS WITH SLEEP-APNEA SYNDROME
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DOI：
10.1016/0002-9149(83)90013-9
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发表时间：
1983-01-01
影响因子：
2.8
通讯作者：
WINKLE, RA
中科院分区：
文献类型：
--
作者：
GUILLEMINAULT, C;CONNOLLY, SJ;WINKLE, RA
本文介绍了1974年至1979年期间，在一个大的睡眠呼吸暂停综合征组（400例患者）中进行的第一次心律失常和传导障碍研究，该研究采用24小时霍尔特ECG和同时记录的下午晚些时候或夜间睡眠期间的多导生理记录仪。在400例患者中，193例（48%）在记录的夜间发生心律失常。心律失常患者的平均呼吸暂停事件数、年龄、体重和睡眠期间最低血氧饱和度无显著差异。最显著的异常是8例患者的非持续性室性心动过速，43例患者的窦性停搏持续2.5-13 s，31例患者的2度房室传导阻滞。75例患者在睡眠期间有频繁的（> 2次/分钟）室性早搏。严重心律失常的患者[50]进行了气管切开术，并在手术后再次进行监测。除室性早搏外，无心律失常。
The 1st study of cardiac arrhythmias and conduction disturbance in a large group (400 patients) with sleep apnea syndrome studied between 1974 and 1979 with 24-h Holter ECG and a simultaneously recorded polygraph during late afternoon or nocturnal sleep is presented. Of the 400, 193 patients (48%) had cardiac arrhythmias during the recorded night. The mean number of apneic events, age, weight and lowest O2 saturation during sleep were not significantly different in those with arrhythmias. The most significant abnormalities were unsustained ventricular tachycardia in 8 patients, sinus arrest that lasted for 2.5-13 s in 43 patients, and 2nd-degree atrioventricular conduction block in 31. Seventy-five had frequent (> 2 beats/min) premature ventricular contractions during sleep. Patients [50] with significant arrhythmias had a tracheostomy and were monitored again after surgery. No arrhythmia was present in these patients except for premature ventricular contractions.