Transcriptomes reveal microRNAs and mRNAs in different photoperiods influencing cashmere growth in goat.
Transcriptomes reveal microRNAs and mRNAs in different photoperiods influencing cashmere growth in goat.
复制标题
DOI：
10.1371/journal.pone.0282772
复制
发表时间：
2023
期刊：
影响因子：
3.7
通讯作者：
中科院分区：
文献类型：
--
作者：
绒山羊具有典型的产绒季节性特征。研究表明，光周期是影响山羊绒周期性生长的主要因素之一，但其分子机制尚不清楚。以内蒙古阿尔巴斯绒山羊为研究对象，探讨不同光周期条件下绒山羊生长的mRNA-microRNA调控机制。采集了光照控制（短光周期）和正常条件（长光周期）下绒山羊的皮肤样品。RNA提取后进行测序。成功构建了差异表达的miRNA和mRNA表达谱。共发现56个已知的差异表达的mRNA（P<0.01）和14个差异表达的microRNA（P<0.05）。microRNAs和mRNAs的关联分析表明，2个差异表达的miRNAs可能是6个差异表达基因的靶基因。这些基因和miRNAs的靶向关系被揭示和验证。总之，光调控技术为促进羊绒生长提供了一条新的途径。研究结果为绒山羊的生长发育提供了参考。
Cashmere goat has a typical characteristic in seasonal growth of cashmere. Studies have shown that one of the main factors affecting the cyclical growth of the cashmere is the photoperiod, however, its molecular mechanism remains unclear. Inner Mongolia Arbas cashmere goat was used to reveal the mRNA-microRNA regulatory mechanisms of cashmere growth in different photoperiod. Skin samples from cashmere goats under light control (short photoperiod) and normal conditions (long photoperiod) were collected. Sequencing was performed after RNA extraction. The differentially expressed miRNA and mRNA expression profiles were successfully constructed. We found 56 significantly differentially expressed known mRNAs (P<0.01) and 14 microRNAs (P<0.05). The association analysis of the microRNAs and mRNAs showed that two differentially expressed miRNAs might be targeted by six differentially expressed genes. Targeting relationships of these genes and miRNAs are revealed and verified. In all, the light control technology provides a new way to promote cashmere growth. Our results provide some references in the cashmere growth and development.
登录
查看更多内容
DOI：
10.1093/bioinformatics/btq033
发表时间：
2010-03-15
期刊：
Bioinformatics (Oxford, England)
影响因子：
--
作者：
Quinlan AR;Hall IM
通讯作者：
Hall IM
影响因子：
2.2
作者：
Wei C;Wang L;Zhang H
通讯作者：
Zhang H
褪黑激素促进绒山羊 (Capra hircus) 次生毛囊生长：来自长非编码和编码 RNA 综合分析的观点
影响因子：
4.3
作者：
Ge, Wei;Wang, Shan-He;Wang, Xin
通讯作者：
Wang, Xin
影响因子：
1.2
作者：
Al-Holou, Shaza N.;Siefker, Edward;Rizzo, William B.
通讯作者：
Rizzo, William B.
DOI：
10.1073/pnas.1215935110
发表时间：
2013-06-04
影响因子：
11.1
作者：
Plikus, Maksim V.;Vollmers, Christopher;Chuong, Cheng-Ming
通讯作者：
Chuong, Cheng-Ming