Fleece growth in Australian cashmere goats. IV. The role of prolactin in the initiation and cessation of cashmere growth
Fleece growth in Australian cashmere goats. IV. The role of prolactin in the initiation and cessation of cashmere growth
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DOI：
10.1071/ar9931051
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发表时间：
1993
影响因子：
1.9
通讯作者：
Wrl Kloren;B. Norton
中科院分区：
文献类型：
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作者：
Wrl Kloren;B. Norton
本试验旨在研究催乳素（Prl）对山羊绒细胞生长启动和维持的影响。从8月至12月或从1月至6月，在两组三只公山羊和三只母山羊中，每周三次肌肉注射溴隐亭（0.5 mg/kg）来抑制Prl分泌。溴隐亭在治疗期间有效地将Prl浓度抑制至低于10 ng/mL。在7月至12月注射的羊绒生长山羊的启动发生在1月后，高后处理水平的PRL开始下降。雄性对照山羊的羊绒生长被认为是正常的羊绒生长的不代表，但在雌性对照山羊的启动发生在12月。溴隐亭处理1月至6月对活性绒生长没有影响。但抑制了尚未开始的羊绒生长。溴隐亭注射对血清T4浓度无影响。结果进行了讨论有关的作用，催乳素的启动，维持和停止羊绒生长。得出的结论是，无论是自然或诱导的峰值PRL浓度与启动（下降的浓度），也可能与羊绒生长（浓度上升）的停止。
An experiment was designed to investigate the effect of prolactin (Prl) on the initiation and maintenance of cashmere growth. Intra-muscular injections of bromocryptine (0.5 mg/kg) three times per week were used to suppress Prl secretion from August to December or from January to June in two groups of three male and three female goats. Bromocryptine effectively suppressed Prl concentrations to below 10 ng/mL for the duration of the treatments. Initiation of cashmere growth goats injected in July to December occurred in January after high post-treatment levels of Prl began to decline. Cashmere growth of male control goats was considered unrepresentative of normal cashmere growth, but initiation in female control goats occurred in December. Bromocryptine treatment from January to June had no effect on active cashmere growth. but inhibited cashmere growth not already initiated. Bromocryptine injections had no effect on serum T4 concentrations. The results are discussed in relation to the role of Prl in the initiation, maintenance and cessation of cashmere growth. It was concluded that either natural or induced peaks of Prl concentrations were associated with the initiation (falling concentrations) and possibly also with the cessation of cashmere growth (rising concentrations).