COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access.
COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access.
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DOI：
10.1007/s11306-015-0810-y
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Steinbeck C
中科院分区：
文献类型：
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作者：
Salek RM;Neumann S;Schober D;Hummel J;Billiau K;Kopka J;Correa E;Reijmers T;Rosato A;Tenori L;Turano P;Marin S;Deborde C;Jacob D;Rolin D;Dartigues B;Conesa P;Haug K;Rocca-Serra P;O'Hagan S;Hao J;van Vliet M;Sysi-Aho M;Ludwig C;Bouwman J;Cascante M;Ebbels T;Griffin JL;Moing A;Nikolski M;Oresic M;Sansone SA;Viant MR;Goodacre R;Günther UL;Hankemeier T;Luchinat C;Walther D;Steinbeck C
代谢组学已成为包括医学、生命科学、生物技术和环境科学在内的一系列研究领域中至关重要的表型分析技术。这就需要在研究小组之间以及潜在的出版商和资助者之间转移实验信息。经过代谢组学标准倡议的初步努力，提出了最低报告标准，其中包括代谢组学数据库的概念。代谢组学的标准和基础设施仍然需要由社区建立，以允许代谢组学数据的存储，交换，比较和再利用。框架方案7欧盟倡议“代谢组学标准协调”（COSMOS）正在为代谢组学数据和元数据开发一个强大的数据基础设施和交换标准。这是为了支持欧洲代谢组学界广泛的代谢组学应用的工作流程，以及更广泛的代谢组学和生物医学界的参与。在这里，我们宣布我们的概念和努力，要求代谢组学社区，学术界和工业界，期刊出版商，软件和硬件供应商，以及那些对全球标准化感兴趣的人（解决缺失的代谢组学本体，复杂的元数据捕获和基于XML的开源数据交换格式）重新参与，加入并致力于更新和实施代谢组学标准。
Metabolomics has become a crucial phenotyping technique in a range of research fields including medicine, the life sciences, biotechnology and the environmental sciences. This necessitates the transfer of experimental information between research groups, as well as potentially to publishers and funders. After the initial efforts of the metabolomics standards initiative, minimum reporting standards were proposed which included the concepts for metabolomics databases. Built by the community, standards and infrastructure for metabolomics are still needed to allow storage, exchange, comparison and re-utilization of metabolomics data. The Framework Programme 7 EU Initiative ‘coordination of standards in metabolomics’ (COSMOS) is developing a robust data infrastructure and exchange standards for metabolomics data and metadata. This is to support workflows for a broad range of metabolomics applications within the European metabolomics community and the wider metabolomics and biomedical communities’ participation. Here we announce our concepts and efforts asking for re-engagement of the metabolomics community, academics and industry, journal publishers, software and hardware vendors, as well as those interested in standardisation worldwide (addressing missing metabolomics ontologies, complex-metadata capturing and XML based open source data exchange format), to join and work towards updating and implementing metabolomics standards.