Relationship between early changes in cerebral blood volume and electrocortical activity after hypoxic-ischemic insult in newborn piglets
Relationship between early changes in cerebral blood volume and electrocortical activity after hypoxic-ischemic insult in newborn piglets
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DOI：
10.1016/j.braindev.2013.08.005
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发表时间：
2014-08-01
影响因子：
1.7
通讯作者：
Itoh, Susumu
中科院分区：
文献类型：
--
作者：
Nakamura, Shinji;Kusaka, Takashi;Itoh, Susumu
背景：据报道，缺氧缺血(HI)后脑血流动力学的早期改变和皮层活动的抑制。然而，这两个参数之间的关系尚不清楚。本研究旨在探讨HI后脑血容量(CBV)和脑Hb血氧饱和度(SCO2)的变化与低幅度积分脑电(AEEG)持续时间的关系。方法：选择出生后24 h内获得的16头新生仔猪(n=3)作为对照。13头仔猪接受了20分钟低波幅AEEG(
Background: Early changes in cerebral hemodynamics and depressed electrocortical activity have been reported after a hypoxic ischemic (HI) insult. However, the relationship between these two parameters is unclear. This study aimed to examine the relationship between changes in cerebral blood volume (CBV) and cerebral Hb oxygen saturation (ScO2) after a HI insult and the low amplitude-integrated electroencephalography (aEEG) duration concomitantly observed. Methods: Sixteen newborn piglets obtained within 24 h of birth were used (n = 3 controls). Thirteen piglets were subjected to a HI insult of 20-min low-amplitude aEEG (