Analysis of magnetic material in the human heart, spleen and liver

Analysis of magnetic material in the human heart, spleen and liver
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DOI:
10.1023/a:1018340920329
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发表时间:
1997-10-01
期刊:
影响因子:
3.5
通讯作者:
Dobson, J
Dobson, J
中科院分区:
生物学3区
文献类型:
--
作者:
GrassiSchultheiss, PP;Heller, F;Dobson, J

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等温剩磁(IRM)采集和交变磁场(A.F.)对从身体上切除的人的心、脾和肝标本进行了退磁分析。在77K和273K下测量了样品的磁性能。在273K下进行A.F.退磁处理。组织分析结果表明,样品中存在铁磁性、细粒、磁性相互作用的颗粒,主要由于磁性,被认为是磁铁矿和/或磁铁矿,超顺磁性颗粒的存在可以从77K下测量的饱和IRM值的增加、273K的测量和77K升温后剩余磁化的衰减来推断,样品中的磁性物质(假设它是磁铁矿或磁铁矿)的浓度从13.7 ng(-1)到343 ng(-1)变化,心脏组织通常具有最高的浓度。这些器官中磁性物质的存在可能对生物成因磁铁矿在人体内的功能有一定的影响。
Isothermal remanent magnetization (IRM) acquisition and alternating field (A.F.) demagnetization analyses were performed on human heart, spleen and liver samples resected from cadavers. The magnetic properties of the samples were measured both at 77K and at 273K. A.F. demagnetization was performed at 273K. Results from the analyses of the tissue indicate the presence of ferromagnetic, fine-grained, magnetically interacting particles which, due primarily to magnetic properties, are thought to be magnetite and/or maghemite, The presence of superparamagnetic particles can be inferred from the increase in saturation IRM values when measured at 77K compared,vith measurements at 273K and the decay of remanent magnetization upon warming from 77K, The concentration of magnetic material (assuming it is magnetite or maghemite) in the samples varies from 13.7 ng g(-1) to 343 ng g(-1), with the heart tissue generally having the highest concentration. The presence of magnetic material in these organs may have implications for the function of biogenic magnetite in the human body.