Accuracy of image fusion using a fixation device for whole-body cancer imaging.
Accuracy of image fusion using a fixation device for whole-body cancer imaging.
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DOI：
10.2214/ajr.184.6.01841960
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发表时间：
2005-06
期刊：
影响因子：
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通讯作者：
Y. Nakamoto;S. Sakamoto;T. Okada;K. Matsumoto;Eiri Minota;H. Kawashima;M. Senda
中科院分区：
文献类型：
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作者：
Y. Nakamoto;S. Sakamoto;T. Okada;K. Matsumoto;Eiri Minota;H. Kawashima;M. Senda
目的探讨以真空垫为固定装置，分别采集正电子发射计算机断层扫描(PET)图像和CT图像的简易图像融合技术的临床可行性。对象和方法44例患者接受18F-2-脱氧-D-葡萄糖(FDG)全身PET扫描，然后用静脉造影剂进行CT扫描。患者被小心地固定在单独成型的垫子中，以便为两次检查提供相同的位置。以膀胱下缘为参照物，在工作站上融合PET和CT图像。根据肝脏和肾脏的生理性摄取和病变的病理摄取来评估配准错误的程度。结果两幅图像肝脏中心点在颅尾方向的平均偏差为6.6±8.7(SD)mm，前后方向为1.9±5.1 mm，左右方向为2.3±7.0 mm。在颅尾方向，右肾为4.7+/-8.7 mm，左肾为4.0+/-8.8 mm。在横隔部以上，活动型和静止型病变中心点的偏差分别为11.7±3.4 mm和10.4±-5.3 mm。横隔部以下，移动性病变为9.7±-2.5 mm，静止性病变为6.9±2.9 mm。结论我们的初步数据表明，该技术是一种简单实用的手动图像融合方法，在临床上是可以接受的。
OBJECTIVE The purpose of this study was to evaluate the clinical feasibility of a simple image fusion technique with PET and CT images acquired separately using a vacuum cushion as a fixation device. SUBJECTS AND METHODS Forty-four patients underwent whole-body PET using 18F-fluoro-2-deoxy-D-glucose (FDG) followed by CT with IV contrast material. The patients were carefully fixed in an individually molded cushion to provide the same positioning for both examinations. The PET and CT images were fused on a workstation by using the lower margin of the urinary bladder as a reference. The degree of misregistration was evaluated for the physiologic uptake of the liver and kidneys and for the pathologic uptake of lesions. RESULTS The average deviation of the center point of the liver between the two images was 6.6 +/- 8.7 (SD) mm in the craniocaudal direction, 1.9 +/- 5.1 mm in the anteroposterior direction, and 2.3 +/- 7.0 mm in the right-left direction. This value in the craniocaudal direction was 4.7 +/- 8.7 mm in the right kidney and 4.0 +/- 8.8 mm in the left kidney. Above the diaphragm, the deviations of the center point of movable and static lesions were 11.7 +/- 3.4 mm and 10.4 +/- 5.3 mm, respectively. Below the diaphragm, those of movable and static lesions were 9.7 +/- 2.5 mm and 6.9 +/- 2.9 mm, respectively. CONCLUSION Our preliminary data indicate that this technique is a simple and practical method for manual image fusion that may be acceptable in clinical settings.