Attention, in and Out: Scalp-Level and Intracranial EEG Correlates of Interoception and Exteroception.
Attention, in and Out: Scalp-Level and Intracranial EEG Correlates of Interoception and Exteroception.
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DOI：
10.3389/fnins.2017.00411
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发表时间：
2017
影响因子：
4.3
通讯作者：
Sedeño L
中科院分区：
文献类型：
--
作者：
García-Cordero I;Esteves S;Mikulan EP;Hesse E;Baglivo FH;Silva W;García MDC;Vaucheret E;Ciraolo C;García HS;Adolfi F;Pietto M;Herrera E;Legaz A;Manes F;García AM;Sigman M;Bekinschtein TA;Ibáñez A;Sedeño L
内感受，即对内脏信号的监测，通常被认为参与了专门用于内部身体感觉的注意机制。事实上，大多数标准化的内感受性任务都需要将注意力集中在内部信号上。然而，该领域的大多数研究未能比较内部驱动和外部驱动过程之间的注意调节，从而盲目探索前者的特异性。在这里，我们通过一种多维方法来解决这个问题，该方法结合了行为测量、通过高密度脑电描记术和颅内记录对事件相关电位和功能连接性的分析。在研究1中，50名健康志愿者进行了心跳检测任务，因为我们记录了三种情况下的心跳诱发电位（HEP）调制：外感受，基础内感受（也称为内感受准确性）和反馈后内感受（有时称为内感受性学习）。在研究2中，为了评估关键的内感受性区域（后额叶、额下回、杏仁核和体感皮层）是否受到外部和内部驱动过程的差异调制，我们分析了这些区域的深部电极的人类颅内记录。与其他技术（如EEG或fMRI）相比，这种独特的技术提供了非常细粒度的时空分辨率。我们发现，在研究1中的两个内感受性条件产生更大的HEP振幅比外感受性。此外，连接分析表明，反馈后内感受，相对于基础内感受，涉及增强连接额叶和后部区域的长距离连接。此外，研究2的结果表明，在基底内感受（宽带：35-110 Hz）和外感受（1-35 Hz）期间，杏仁核、躯体感觉皮层和额下回的振荡之间存在差异。总之，这项工作提供了收敛的证据的特异性和动态的注意机制参与内感受。
Interoception, the monitoring of visceral signals, is often presumed to engage attentional mechanisms specifically devoted to inner bodily sensing. In fact, most standardized interoceptive tasks require directing attention to internal signals. However, most studies in the field have failed to compare attentional modulations between internally- and externally-driven processes, thus probing blind to the specificity of the former. Here we address this issue through a multidimensional approach combining behavioral measures, analyses of event-related potentials and functional connectivity via high-density electroencephalography, and intracranial recordings. In Study 1, 50 healthy volunteers performed a heartbeat detection task as we recorded modulations of the heartbeat-evoked potential (HEP) in three conditions: exteroception, basal interoception (also termed interoceptive accuracy), and post-feedback interoception (sometimes called interoceptive learning). In Study 2, to evaluate whether key interoceptive areas (posterior insula, inferior frontal gyrus, amygdala, and somatosensory cortex) were differentially modulated by externally- and internally-driven processes, we analyzed human intracranial recordings with depth electrodes in these regions. This unique technique provides a very fine grained spatio-temporal resolution compared to other techniques, such as EEG or fMRI. We found that both interoceptive conditions in Study 1 yielded greater HEP amplitudes than the exteroceptive one. In addition, connectivity analysis showed that post-feedback interoception, relative to basal interoception, involved enhanced long-distance connections linking frontal and posterior regions. Moreover, results from Study 2 showed a differentiation between oscillations during basal interoception (broadband: 35–110 Hz) and exteroception (1–35 Hz) in the insula, the amygdala, the somatosensory cortex, and the inferior frontal gyrus. In sum, this work provides convergent evidence for the specificity and dynamics of attentional mechanisms involved in interoception.
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影响因子：
16.6
作者：
Dastjerdi, Mohammad;Ozker, Muge;Foster, Brett L.;Rangarajan, Vinitha;Parvizi, Josef
通讯作者：
Parvizi, Josef
影响因子：
2.6
作者：
Chen J;Dastjerdi M;Foster BL;LaRocque KF;Rauschecker AM;Parvizi J;Wagner AD
通讯作者：
Wagner AD
DOI：
10.1093/cercor/bhv076
发表时间：
2015-11
期刊：
Cerebral cortex (New York, N.Y. : 1991)
影响因子：
--
作者：
Canales-Johnson A;Silva C;Huepe D;Rivera-Rei Á;Noreika V;Garcia Mdel C;Silva W;Ciraolo C;Vaucheret E;Sedeño L;Couto B;Kargieman L;Baglivo F;Sigman M;Chennu S;Ibáñez A;Rodríguez E;Bekinschtein TA
通讯作者：
Bekinschtein TA
影响因子：
9.8
作者：
Dressler, O;Schneider, G;Kochs, EF
通讯作者：
Kochs, EF
影响因子：
2.9
作者：
Cohen MX
通讯作者：
Cohen MX