Changes in human fetal oxygenation during maternal hyperoxia as estimated by BOLD MRI
Changes in human fetal oxygenation during maternal hyperoxia as estimated by BOLD MRI
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DOI：
10.1002/pd.4025
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发表时间：
2013-02-01
影响因子：
3
通讯作者：
Uldbjerg, Niels
中科院分区：
文献类型：
--
作者：
Sorensen, Anne;Peters, David;Uldbjerg, Niels
目的血氧水平依赖（BOLD）磁共振成像（MRI）信号的变化与胎儿氧合变化密切相关。在这项研究中，我们的目的是探讨人类胎儿氧在母体高氧的变化，通过使用无创的BOLD MRI技术。方法选择8例孕28 ~ 34周的健康孕妇。通过使用面部氧气面罩，我们诱导母体高氧，并测量所选胎儿器官的BOLD MRI信号变化。结果胎儿多个器官的BOLD信号明显增强（P
Objective Changes in blood oxygen level dependent (BOLD) magnetic resonance imaging (MRI) signal are closely related to changes in fetal oxygenation. In this study, we aimed to investigate the changes in human fetal oxygenation during maternal hyperoxia by using the non-invasive BOLD MRI technique. Method Eight healthy pregnant women in gestational week 28 to 34 were included. With the use of a facial oxygen mask, we induced maternal hyperoxia and measured changes in the BOLD MRI signal of selected fetal organs. Results In a number of fetal organs, the BOLD MRI signal increased significantly (P