ETIOLOGICAL AND PROGNOSTIC CORRELATES OF SITE OF MYOCARDIAL-INFARCTION
ETIOLOGICAL AND PROGNOSTIC CORRELATES OF SITE OF MYOCARDIAL-INFARCTION
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DOI：
10.1093/eurheartj/9.7.734
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发表时间：
1988-07-01
影响因子：
39.3
通讯作者：
ROBINSON, K
中科院分区：
文献类型：
--
作者：
BOURKE, S;CONROY, RM;ROBINSON, K
这是一项对745例连续入院的首次心肌梗死患者的梗死部位、危险因素和住院结果之间关系的研究。前侧梗死患者从未吸烟的可能性明显高于下侧梗死患者。他们有较高的高血压患病率和较高的平均胆固醇水平。前侧梗死患者的住院预后较差，死亡率和并发症发生率明显较高。房室传导阻滞在下端梗死中更为常见。非q波性梗死并发症发生率低于q波性梗死。在q波梗死和非q波梗死之间，危险因素水平没有差异。前梗死和下梗死大小相似。非q波梗死明显较小。logistic回归分析显示，住院死亡率与吸烟呈负相关，与心肌酶峰值呈正相关。当校正这些因素后，任何梗死部位对死亡率的影响都被消除了。我们的数据表明，与前壁心肌梗死相关的不良预后与病因差异有关，而与梗死大小无关。
This is a study of relationship between the site of infarction and both risk factors and in-hospital outcome in 745 consecutive patients admitted with a first myocardial infarction. Patients with anterior infarctions were significantly more likely never to have smoked than patients with inferior infarctions. They had a higher prevalence of hypertension and a higher mean cholesterol level. Inhospital prognosis was worse in anterior infarctions, with significantly higher rates of death and complications. Atrioventricular blocks were more common in inferior infarctions. Non-Q-wave infarctions had a lower incidence of complications than Q-wave infarctions. There was no difference in risk factor levels between Q-wave and non-Q-wave infarctions. Anterior and inferior infarctions were of similar size. Non-Q-wave infarctions were significantly smaller. A logistic regression showed a negative relationship between in-hospital mortality and smoking, and a positive one with peak caridac enzyme levels. Any effect of site of infarction on mortality was eliminated when corrected for these factors. Our data indicate that the adverse prognosis associated with anterior myocardial infarction is related to differences in aetiology rather than to infarction size.