Lymphocytes infiltrating human breast cancers lack K-cell activity and show low levels of NK-cell activity.

Lymphocytes infiltrating human breast cancers lack K-cell activity and show low levels of NK-cell activity.
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DOI:
10.1038/bjc.1981.167
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发表时间:
1981-08
影响因子:
8.8
通讯作者:
Ashby, J
Ashby, J
中科院分区:
医学1区
文献类型:
--
作者:
Eremin, O;Coombs, R R;Ashby, J

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Lymphocytes infiltrating human primary mammary carcinomas lack ADCC and show low levels of natural cytotoxicity. The peripheral blood lymphocytes, however, show a variable but prominent level of cytotoxicity. Lymphocyte preparations from breast tumours, when mixed with autologous blood lymphocytes, significantly suppress their prominent killer- (K- and NK-) cell activities.