The Cambridge Semantic Memory Test Battery: Detection of semantic deficits in semantic dementia and Alzheimer's disease
The Cambridge Semantic Memory Test Battery: Detection of semantic deficits in semantic dementia and Alzheimer's disease
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DOI：
10.1080/13554790903405693
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发表时间：
2010-01-01
期刊：
影响因子：
0.8
通讯作者：
Hodges, John R.
中科院分区：
文献类型：
--
作者：
Adlam, Anna-Lynne R.;Patterson, Karalyn;Hodges, John R.
这项研究的目的是(A)探索剑桥语义记忆测试组合的更新和扩展版本的实用性，并使其更广泛地可用，以及(B)将该组合与其他测试结合使用，以表征几种不同形式的进行性认知障碍的特征：语义性痴呆(SD，n=15)、轻度认知障碍(MCI，n=7)、已建立的阿尔茨海默病(AD)(n=8)，所有这些都与正常对照组(n=45)相比较。语义组在探索语义缺陷的本质方面很有用；然而，它本身并不能提供AD和SD患者之间的敏感区分。为了更好地描述与SD和AD相关的认知特征，建议进行包括情景记忆和视觉空间能力测量以及语义组的评估。
The aims of this study were (a) to explore the utility of, and make more widely available, an updated and extended version of the Cambridge Semantic Memory test battery, and (b) to use this battery in conjunction with other tests to characterise the profile of several different forms of progressive cognitive impairment: semantic dementia (SD, n = 15), mild cognitive impairment (MCI, n = 7), established Alzheimer's disease (AD) (n = 8), all in comparison to normal controls (n = 45). The semantic battery is useful in a variety of ways for exploring the nature of semantic deficits; on its own, however, it does not provide sensitive differentiation between patients with AD and SD. An assessment including measures of episodic memory and visuospatial abilities as well as the semantic battery is recommended for good characterisation of the cognitive profiles associated with SD and AD.