Black tea reduces uric acid and C-reactive protein levels in humans susceptible to cardiovascular diseases
Black tea reduces uric acid and C-reactive protein levels in humans susceptible to cardiovascular diseases
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DOI：
10.1016/j.tox.2009.11.024
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发表时间：
2010-11-28
期刊：
影响因子：
4.5
通讯作者：
Aruoma, Okezie I.
中科院分区：
文献类型：
--
作者：
Bahorun, Theeshan;Luximon-Ramma, Amitabye;Aruoma, Okezie I.
在一项前瞻性随机对照研究中，评估了红茶对缺血性心脏病易感人群尿酸（UA）和C反应蛋白（CRP）水平的影响。研究组每天饮用9克红茶（相当于三杯茶），持续12周，不含添加剂，然后进行3周的清洗（对照组饮用等量的热水）。红茶消费诱导高尿酸基线组>6 mg/dL的显著降低8.5%; p << 0.05. For men and women in the base line group >7 mg/dL，分别降低9.4%和7.1%。在低基线血清尿酸水平中，男性和女性分别增加了3.7%和15%，无显著性差异。C反应蛋白>3 mg/L的高危组，男性和女性分别下降53.4%和41.1%。在此范围内，未补充组的变化为男性减少3.7%，女性增加2.9%。饮茶相关的血浆尿酸和C-反应蛋白水平的降低可能有益于心血管事件高风险人群，并可能增强药物治疗。(C)2009爱思唯尔爱尔兰有限公司保留所有权利。
The effect of black tea on the level of uric acid (UA) and C-reactive proteins (CRP) in humans susceptible to ischemic heart diseases was assessed in a prospective randomized controlled study. The study group consumed 9g of black tea (equivalent to three cups of tea) daily for 12 weeks without additives followed by a 3-week wash-out (with control group consuming equivalent volume of hot water). Black tea consumption induced a highly significant decrease in the high uric acid baseline groups >6 mg/dL by 8.5%; p < 0.05. For men and women in the base line group >7 mg/dL, the decrease was 9.4% and 7.1%, respectively. In the low baseline serum uric acid levels there was a non-significant increase of 3.7% and 15% in men and women, respectively. C-reactive protein in the high risk group >3 mg/L was significantly decreased by 53.4% and 41.1% in men and women, respectively. For the non-supplemented group in this range the changes were 3.7% decrease for men and 2.9% increase for women. Tea supplementation-associated decrease in plasma uric acid and C-reactive protein levels may benefit humans at high risk of cardiovascular events and may augment drug therapy. (C) 2009 Elsevier Ireland Ltd. All rights reserved.