Rethinking screening

Rethinking screening
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DOI:
10.1038/nchembio.303
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发表时间:
2010-03-01
影响因子:
14.8
通讯作者:
Kodadek, Thomas
Kodadek, Thomas
中科院分区:
生物学1区
文献类型:
--
作者:
Kodadek, Thomas

文献摘要

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生物活性化合物最常通过高通量筛选活动进行鉴定。本文讨论了最流行的筛选方法的优点和缺点,以及从它们衍生的化合物的效用。
Bioactive compounds are most frequently identified via high-throughput screening campaigns. This article discusses the strengths and weaknesses of the most popular screening approaches and the utility of compounds derived from them.