Predictability of motor outcome according to the time of diffusion tensor imaging in patients with cerebral infarct
Predictability of motor outcome according to the time of diffusion tensor imaging in patients with cerebral infarct
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DOI：
10.1007/s00234-011-0972-x
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发表时间：
2012-07-01
期刊：
影响因子：
2.8
通讯作者：
Jang, Sung Ho
中科院分区：
文献类型：
--
作者：
Kwon, Yong Hyun;Jeoung, Yong Jae;Jang, Sung Ho
弥散张量成像纤维束成像 (DTT) 对运动结果的可预测性可能因 DTT 时间的不同而不同。我们试图通过分析放射冠 (CR) 梗塞患者 DTT 上的皮质脊髓束 (CST) 完整性，根据扩散张量成像 (DTI) 时间来比较运动结果的可预测性。 招募了 71 名连续 CR 梗塞偏瘫患者。对受影响肢体的运动功能进行了两次测量：发病时和发病后 6 个月时。根据DTI时间将患者分为两组：脑卒中发病14天内早期扫描组（ES组）；晚期扫描组（LS组）15-28天。将运动结果与 DTT 上的 CST 完整性进行比较。在逻辑回归模型中，根据 DTI 的扫描时间和 DTT 上的 CST 完整性来预测运动预后。根据单独的回归分析，发现晚期组的 CST 完整性可以预测 MI 评分（OR = 14.000，95% CI = 3.194-61.362，p < 0.05），而早期组的 CST 完整性不能预测 MI 评分。就阳性和阴性预测性而言，我们发现较晚（发病后 15-28 天）扫描的患者的 DTT 对运动结果的预测性更好与早期（发病后 1-14 天）接受扫描的患者相比。
Predictability of diffusion tensor imaging tractography (DTT) for motor outcome can differ according to the time of DTT. We attempted to compare the predictability for motor outcome according to the time of diffusion tensor imaging (DTI) by analyzing the corticospinal tract (CST) integrity on DTT in patients with corona radiata (CR) infarct.Seventy-one consecutive hemiparetic patients with CR infarct were recruited. Motor function of the affected extremities was measured twice: at onset and at 6 months from onset. According to the time of DTI, patients were classified into two groups: the early scanning group (ES group) within 14 days since stroke onset; and the late scanning group (LS group) 15-28 days. Motor outcome was compared with the CST integrity on DTT.Motor prognosis was predicted from scan time of DTI and the CST integrity on DTT in the logistic regression model. According to separate regression analysis, the CST integrity of the late group was found to predict MI score (OR = 14.000, 95% CI = 3.194-61.362, p < 0.05), whereas the CST integrity of the early group was not found to predict MI score.In terms of both positive and negative predictabilities, we found that predictability of DTT for motor outcome was better in patients who were scanned later (15-28 days after onset) than in patients who were scanned earlier (1-14 days after onset).