PEI therapy for thyroid lesions.
PEI therapy for thyroid lesions.
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PEI 治疗甲状腺病变。
DOI：
10.1016/s0753-3322(02)00214-7
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发表时间：
2002
期刊：
影响因子：
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通讯作者：
N. Fukunari
中科院分区：
文献类型：
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作者：
N. Fukunari
PEI治疗已作为一种新的治疗策略应用于临床囊性病变和自主功能性甲状腺结节。目前正在考虑的一些其他适应症包括冷良性肿瘤和无法手术的晚期甲状腺癌，以及Graves病术后复发。从1999年到2001年，我们用PEI治疗了2323例甲状腺疾病患者。PEI通常在囊性病变的情况下在超声引导下施用，并且在甲状腺的实体病变的情况下在彩色多普勒引导下施用，目的是减弱肿瘤血流。因此，在我院接受PEI治疗的2323例病例中，1989例（85.6%）被分类为有效缓解（ER）或部分缓解（PR）。没有重大并发症，如喉返神经麻痹，无法控制的疼痛，出血或甲状腺毒症。我们的研究结果还强调了使用彩色多普勒引导控制乙醇注射量的重要性，以完全衰减肿瘤血管所需的最低限度。
PEI therapy has been applied clinically as a new treatment strategy for cystic lesions and autonomous functioning nodules of the thyroid. Some additional indications currently under consideration include cold benign tumors and inoperable advanced cancer of the thyroid, and postoperative recurrence of Graves' disease. At our institution, we have treated 2323 patients with thyroid disease by PEI therapy from 1999 to 2001. PEI is usually administered under ultrasound guidance in cases of cystic lesions, and under color-Doppler guidance in cases of solid lesions of the thyroid, with the goal of attenuating tumor blood flow. In consequence, of the total 2323 cases who received PEI therapy at our hospital, 1989 (85.6%) were classified as showing an effective response (ER) or partial response (PR). There were no major complications, such as recurrent laryngeal nerve palsy, uncontrollable pain, bleeding, or thyrotoxicosis. Our results also emphasize the importance of the use of color-Doppler guidance for control of the injection volume of ethanol to the minimum required for completely attenuating the tumor vascularity.