E-cigarette use and respiratory disorder in an adult sample
E-cigarette use and respiratory disorder in an adult sample
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DOI：
10.1016/j.drugalcdep.2018.10.004
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发表时间：
2019-01-01
影响因子：
4.2
通讯作者：
Tam, Elizabeth K.
中科院分区：
文献类型：
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作者：
Wills, Thomas A.;Pagano, Ian;Tam, Elizabeth K.
目标：关于电子烟与健康指数之间关系的证据很少。我们根据行为风险因素监测调查 (BRFSS) 的数据，调查了成人电子烟使用与诊断出的呼吸系统疾病之间的关联。方法：2016 年夏威夷 BRFSS 是一项横断面随机拨号电话调查，共有 8087 名参与者；平均年龄为55岁。询问有关电子烟使用、吸烟以及被健康专业人员诊断为 (a) 哮喘或 (b) 慢性阻塞性肺病的项目。多变量分析测试了电子烟使用与控制吸烟以及人口、身体和社会心理变量的呼吸变量之间的关联。结果：控制协变量和吸烟后，在总样本中，电子烟使用与慢性肺病存在显着相关性（AOR = 2.58，CI 1.36-4.89，p < 0.01），并且与非吸烟者中的哮喘显着相关（AOR = 1.33，CI） 1.00-1.77，p < 0.05）。非吸烟者中的这种关联比吸烟者中的关联更强。基于相对风险和绝对风险的分析结果相似。吸烟者、女性以及超重、经济压力和二手烟暴露的人患呼吸系统疾病的可能性也更大。结论：这是第一项表明电子烟使用与慢性呼吸系统疾病存在显着独立关联的研究。该数据的几个方面与患有呼吸系统疾病的人使用电子烟戒烟的可能性不一致。讨论了可能将电子烟使用与呼吸道症状联系起来的理论机制。
Objectives: Little evidence is available on the association of e-cigarettes with health indices. We investigated the association of e-cigarette use with diagnosed respiratory disorder among adults in data from the Behavioral Risk Factor Surveillance Survey (BRFSS).Methods: The 2016 Hawaii BRFSS, a cross-sectional random-dial telephone survey, had 8087 participants; mean age was 55 years. Items asked about e-cigarette use, cigarette smoking, and being diagnosed by a health professional with (a) asthma or (b) chronic obstructive pulmonary disease. Multivariable analyses tested associations of e-cigarette use with the respiratory variables controlling for smoking and for demographic, physical, and psychosocial variables.Results: Controlling for the covariates and smoking there was a significant association of e-cigarette use with chronic pulmonary disorder in the total sample (AOR = 2.58, CI 1.36-4.89, p < 0.01) and a significant association with asthma among nonsmokers (AOR = 1.33, CI 1.00-1.77, p < 0.05). The associations were stronger among nonsmokers than among smokers. Results were similar for analyses based on relative risk and absolute risk. There was also a greater likelihood of respiratory disorder for smokers, females, and persons with over-weight, financial stress, and secondhand smoke exposure.Conclusions: This is the first study to show a significant independent association of e-cigarette use with chronic respiratory disorder. Several aspects of the data are inconsistent with the possibility that e-cigarettes were being used for smoking cessation by persons with existing respiratory disorder. Theoretical mechanisms that might link e-cigarettes use and respiratory symptoms are discussed.