Heavy silicone oil as a long-term endotamponade agent for complicated retinal detachments.

Heavy silicone oil as a long-term endotamponade agent for complicated retinal detachments.
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DOI:
10.1155/2014/136031
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发表时间:
2014
影响因子:
--
通讯作者:
Maia M
Maia M
中科院分区:
生物学3区
文献类型:
--
作者:
Prazeres J;Magalhães O Jr;Lucatto LF;Navarro RM;Moraes NS;Farah ME;Maia A;Maia M

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我们回顾性评价了25例患者的25只眼睛使用重硅油(HSO)作为长期眼内填充剂治疗下方PVR引起的复杂RD。患者接受PPV和Oxane HD注射作为内部填塞剂。比较HSO取出组和HSO未取出组术前和术后第1个月、第6个月和末次访视时的BCVA。使用Wilcoxon检验进行统计学计算。11例患者在平均26.55 ± 21.38个月后取出HSO。14眼HSO残留在玻璃体腔内,PVR复发率高(平均随访11.07 ± 7.44个月)。解剖成功率为92%。在头6个月内,未移除HSO的组的BCVA显著改善。在取出油的患者中,BCVA在1个月后有所改善。油乳化是52%眼睛中最常见的不良反应。HSO是治疗复杂孔源性牵拉性RD合并PVR的有效填塞物。HSO可以在眼睛中长时间保留,具有相对的耐受性和安全性。
We retrospectively evaluated a heavy silicone oil (HSO) as a long-term intraocular endotamponade agent to treat complicated RD by inferior PVR in 25 eyes of 25 patients. Patients underwent PPV and injection of Oxane HD as an internal tamponade agent. A comparison of preoperative and postoperative BCVA at month 1, month 6, and last visit was made in the group in which HSO was removed and in the group in which HSO was not removed. Statistical calculations were performed using the Wilcoxon test. The HSO was removed from 11 patients after a mean of 26.55 ± 21.38 months. The HSO remained inside the vitreous cavity in 14 eyes due to a high chance of PVR recurrence (mean follow-up period, 11.07 ± 7.44 months). Anatomic success was achieved in 92%. The BCVA in the group, in which HSO was not removed, improved significantly during the first 6 months. Among the patients who had the oil removed, there was improvement in BCVA after 1 month. Oil emulsification was the most common adverse effect in 52% of eyes. HSO is an effective tamponade in complex rhegmatogenous and tractional RD complicated by PVR. HSO can remain in the eye for long periods with relative tolerability and safety.
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