Decrease in the numbers of mechanoreceptors in rabbit ACL: the effects of ageing
Decrease in the numbers of mechanoreceptors in rabbit ACL: the effects of ageing
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DOI：
10.1007/s00167-005-0673-2
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发表时间：
2006-04-01
影响因子：
3.8
通讯作者：
Demirel, HA
中科院分区：
文献类型：
--
作者：
Aydog, ST;Korkusuz, P;Demirel, HA
有人提出，机械感受器的数量与本体感觉功能之间存在正相关关系。另一方面，正常的衰老过程与本体感觉缺陷有关。这项研究旨在检验衰老导致机械感受器数量减少的假设。摘除14只雄性兔（2月龄，n=5；12月龄，n=4；60月龄，n=5）的前十字韧带，统计Ruffini、Pacini和高尔基腱样受体的总数。结果，机械感受器的数量，尤其是鲁菲尼受体的数量，随着年龄的增长而减少（p < 0.05）。年龄的增加与机械感受器形态的变化有关。总之，衰老会导致机械感受器数量减少和形态变化。
It is proposed that there is a positive correlation between the numbers of mechanoreceptors and proprioceptive function. On the other hand, normal aging process is associated with deficits in proprioception. This study is designed to test the hypothesis that aging resulted in decreased numbers of mechanoreceptors. Anterior cruciate ligaments of 14 male rabbits (2 months, n=5; 12 months, n=4 and 60 months, n=5) were extracted and the total numbers of Ruffini, Pacini and Golgi tendon-like receptors were accounted. As a result, the numbers of mechanoreceptors, especially Ruffini receptors, decreased with aging (p < 0.05). Increased age was associated with changes in the morphology of mechanoreceptors. In conclusion, aging results in both diminished numbers and changed morphology of mechanoreceptors.