Infectious agents associated with respiratory diseases in 125 farrow-to-finish pig herds: A cross-sectional study
Infectious agents associated with respiratory diseases in 125 farrow-to-finish pig herds: A cross-sectional study
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DOI：
10.1016/j.vetmic.2011.12.015
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发表时间：
2012-05-25
影响因子：
3.3
通讯作者：
Rose, N.
中科院分区：
文献类型：
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作者：
Fablet, C.;Marois-Crehan, C.;Rose, N.
在125个仔猪至育成猪群中进行了一项研究，以评估呼吸系统疾病相关病原体之间的关系，并将这些发现与屠宰时呼吸系统疾病、肺炎和胸膜炎的临床体征联系起来。对每个猪群（4、10、16和22周龄猪）的4个不同批次进行临床检查和采样。采用血清学和PCR方法检测猪肺炎支原体、胸膜肺炎放线杆菌、猪流感病毒（SIV）、猪繁殖与呼吸综合征病毒（PRRSV）和猪圆环病毒2型（PCV 2）。在屠宰场对胸膜炎样肉眼病变和胸膜炎进行评分。结果表明，4、10和16周龄时PCV2 PCR阳性猪的百分比与M PCR阳性猪的百分比相关。在这个年龄段的时候，另一方面，在10、16和22周时具有抗PRRSV抗体的猪的百分比与M血清阳性的猪的百分比正相关。22周时，猪流感疫苗接种后，具有抗SIV H1N1和SIV H1N2抗体的猪的百分比以及A.胸膜肺炎血清2型研究结果还表明，在所研究的五种病原体中，M.猪肺炎、猪繁殖与呼吸综合征和猪流感病毒H1N1是肺炎样肉眼病变的主要病原体，尽管PCV 2可能起作用。A.与繁殖与呼吸综合征相关的胸膜肺炎血清型2与广泛性胸膜炎显着相关。通过采取措施，包括适当的管理做法来控制这些病原体，可以大大减少呼吸道疾病。(C)2011 Elsevier B.V.保留所有权利。
A study was carried out in 125 farrow-to-finish pig herds to assess the relationships between pathogens involved in respiratory disorders and to relate these findings to clinical signs of respiratory diseases and pneumonia and pleuritis at slaughter. Clinical examination and sampling were carried out on four different batches in each herd (pigs aged 4, 10, 16 and 22 weeks). Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, swine influenza viruses (SIV), porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2) were detected by serological or PCR tests. Pneumonia-like gross lesions and pleuritis were scored at the slaughterhouse. The results indicate that the percentage of pigs PCR-positive for PCV2 at 4, 10 and 16 weeks old was associated with the percentage of pigs PCR-positive for M. hyopneumoniae at these ages. On the other hand, the percentage of pigs with antibodies against PRRSV at 10, 16 and 22 weeks was positively correlated with the percentage of pigs seropositive for M. hyopneumoniae at 22 weeks, with the percentage of pigs with antibodies against SIV H1N1 and SIV H1N2 and the percentage of pigs sero-positive for A. pleuropneumoniae serotype 2. The findings also indicate that, within the five studied pathogens, M. hyopneumoniae, PRRSV and SIV H1N1 are the major pathogens involved in pneumonia-like gross lesions even though PCV2 may play a role. A. pleuropneumoniae serotype 2, in association with PRRSV, is significantly associated with extensive pleuritis. Respiratory diseases could be significantly reduced by implementing measures including appropriate management practices to control these pathogens. (C) 2011 Elsevier B.V. All rights reserved.