Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
复制标题
DOI：
10.1161/01.atv.20.6.1595
复制
发表时间：
2000-06-01
影响因子：
8.7
通讯作者：
Matsuzawa, Y
中科院分区：
文献类型：
--
作者：
Hotta, K;Funahashi, T;Matsuzawa, Y
脂联素是一种新的脂肪特异性蛋白，广泛存在于血液循环中，具有抗动脉粥样硬化的特性。我们分析了年龄和体重指数(BMI)匹配的非糖尿病和2型糖尿病合并和不合并冠状动脉病变(CAD)的患者的血浆脂联素浓度。糖尿病非冠心病组血浆脂联素水平低于非糖尿病组(男性6.6+/-0.4比7.9+/-0.5 mU/m L，女性7.6+/-0.7比11.7+/-1.0 m u/m L；P
Adiponectin is a novel, adipose-specific protein abundantly present in the circulation, and it has antiatherogenic properties. We analyzed the plasma adiponectin concentrations in age- and body mass index (BMI)-matched nondiabctic and type 2 diabetic subjects with and without coronary artery disease (CAD). Plasma levels of adiponectin in the diabetic subjects without CAD were lower than those in nondiabetic subjects (6.6+/-0.4 versus 7.9+/-0.5 mu g/mL in men, 7.6+/-0.7 versus 11.7+/-1.0 mu g/mL in women; P