The management of anemia in pediatric peritoneal dialysis patients
The management of anemia in pediatric peritoneal dialysis patients
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小儿腹膜透析患者贫血的治疗
DOI：
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发表时间：
2003
期刊：
影响因子：
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通讯作者：
C. Schröder
中科院分区：
文献类型：
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作者：
C. Schröder
贫血在慢性肾功能衰竭中很常见。成人贫血的诊断和治疗指南是可用的。关于儿童腹膜透析的诊断和治疗，欧洲儿科腹膜透析工作组(EPPWG)已经制定了指南。经过彻底的诊断检查后，治疗的目标应该是至少达到11微克/L的目标血红蛋白浓度。这可以通过给予促红细胞生成素和铁制剂来实现。尽管有足够的证据支持腹膜腔内应用促红细胞生成素，但大多数儿科肾病医生仍通过皮下途径应用促红细胞生成素。最好将铁作为口服制剂来处方。必须对这些儿童的营养摄入量给予足够的重视。在儿童腹膜透析患者的贫血治疗中，肉碱的补充没有立足之地。
Anemia is common in chronic renal failure. Guidelines for the diagnosis and treatment of anemia in adult patients are available. With respect to the diagnosis and treatment in children on peritoneal dialysis, the European Pediatric Peritoneal Dialysis Working Group (EPPWG) has produced guidelines. After a thorough diagnostic work-up, treatment should aim for a target hemoglobin concentration of at least 11 g/l. This can be accomplished by the administration of erythropoietin and iron preparations. Although there is sufficient evidence to advocate the intraperitoneal administration of erythropoietin, most pediatric nephrologists still apply erythropoietin by the subcutaneous route. Iron should preferably be prescribed as an oral preparation. Sufficient attention has to be paid to the nutritional intake in these children. There is no place for carnitine supplementation in the treatment of anemia in pediatric peritoneal dialysis patients.