An epigenetic "LINK(RNA)" to pathological cardiac hypertrophy.
An epigenetic "LINK(RNA)" to pathological cardiac hypertrophy.
复制标题
与病理心脏肥大的表观遗传“联系(RNA)”。
DOI:
10.1016/j.cmet.2014.09.011
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发表时间:
2014-10-07
期刊:
影响因子:
29
通讯作者:
Wang DZ
中科院分区:
文献类型:
--
作者:
Liu J;Wang DZ
Reinduction of fetal gene expression is characteristic of the failing adult heart. demonstrate that a novel cluster of long noncoding RNAs, Myheart, protects the heart from pathological hypertrophy, involving a negative-feedback molecular circuit with the epigenetic Brg1 complex to inhibit fetal-gene reactivation.