Simple palladium(II) precatalyst for Suzuki-Miyaura couplings: Efficient reactions of benzylic, aryl, heteroaryl, and vinyl coupling partners
Simple palladium(II) precatalyst for Suzuki-Miyaura couplings: Efficient reactions of benzylic, aryl, heteroaryl, and vinyl coupling partners
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DOI：
10.1021/ol702291r
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发表时间：
2007-12-20
期刊：
影响因子：
5.2
通讯作者：
Taylor, Richard J. K.
中科院分区：
文献类型：
--
作者：
Burns, Michael J.;Fairlamb, Ian J. S.;Taylor, Richard J. K.
TRANS-PDBR(N-Succ)(PPh_3)(2)(1)是一种普遍有效的催化苯基卤化物与芳基或杂芳基硼酸发生Suzuki-Miyaura偶联反应的预催化剂。取代的芳基卤化物和卤代环烯能以优异的产率与芳基或乙烯基硼酸交叉偶联。还演示了催化剂的回收利用。
trans-PdBr(N-Succ)(PPh3)(2) (1) is a universally effective precatalyst for Suzuki-Miyaura cross-couplings of benzylic halides with aryl- or heteroarylboronic acids. Substituted aryl halides and halogenated cyclic enones can be cross-coupled with aryl- or vinylboronic acids in excellent yields. Catalyst recycling is also demonstrated.