CONTRAST SENSITIVITY IS INCREASED IN A CASE OF NONPARKINSONIAN FREEZING GAIT
CONTRAST SENSITIVITY IS INCREASED IN A CASE OF NONPARKINSONIAN FREEZING GAIT
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DOI：
10.1212/wnl.42.1.189
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发表时间：
1992-01-01
期刊：
影响因子：
9.9
通讯作者：
SERRATRICE, G
中科院分区：
文献类型：
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作者：
MESTRE, D;BLIN, O;SERRATRICE, G
我们测量了一名60岁男性的时空对比敏感性和步态变量，他有自发性的冻结步态发作，没有任何僵硬或震颤的迹象。触发冻结的一个主要因素是视觉空间的特征，因为冻结发生在自发行走和通过孔洞时，而不是在闭着眼睛行走时。当在患者前方的地面上放置最佳间隔的横条纹时，运动的开始和维持将大大促进。另一方面，与老年对照相比，该患者对中低时空频率的对比敏感度有所提高。这些数据表明，对视觉刺激和视觉环境改变的过度敏感，与异常的眼运动行为相关，可能是导致冻结步态现象的一个因素，这种现象可以被称为“过度敏感制动”，并被认为是一种感觉运动障碍。
We measured spatiotemporal contrast sensitivity and gait variables in a 60-year-old man who had spontaneous episodes of freezing gait without any sign of rigidity or tremor. One major factor triggering freezing was the characteristics of visual space, as freezing episodes occurred during spontaneous walking and passing through apertures and never during walking with eyes closed. Initiation and maintenance of locomotion were greatly facilitated when transverse stripes with optimal intervals were placed on the ground in front of the patient. On the other hand, contrast sensitivity to low-to-intermediate spatiotemporal frequencies was increased in this patient when compared with that of elderly controls. These data suggest that hypersensitivity to visual stimulation and to modifications of the visual environment, associated with abnormal ocular motor behavior, can be one factor leading to the freezing gait phenomenon, which could be called "hypersensitivity braking" and be considered as a sensorimotor disorder.