Characterization of basket-forceps-type micro-flow-sensor for breathing measurements in small airway
Characterization of basket-forceps-type micro-flow-sensor for breathing measurements in small airway
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DOI：
10.1007/s00542-016-3265-9
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发表时间：
2017-01
期刊：
影响因子：
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通讯作者：
N. Harada;Y. Hasegawa;R. Ono;M. Matsushima;T. Kawabe;M. Shikida
中科院分区：
文献类型：
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作者：
N. Harada;Y. Hasegawa;R. Ono;M. Matsushima;T. Kawabe;M. Shikida
我们以前提出了一种篮钳式流量传感器，在篮钳上安装一个柔性的热流传感器，将流量传感器固定在呼吸道的内表面上。为了防止气流往复流动，篮钳式流量传感器具有不对称的结构；因此，我们研究了篮钳式流量传感器在呼气和吸气两种气流条件下的特性。热流量传感器被制作在柔性聚酰亚胺薄膜上，并安装在篮钳的导向管上。两个加热器及其电气布线模式被设计为在加热器上产生对称的热分布。实验评估了转鼓结构和导流管对流量测量的影响，证实它们不会影响传感器的输出。相反，传感器的输出随着管径的增加而减少，这是由于平均流速随着管径的增加而减小。因此，我们进行了一种程序，以建立在任意管径下的校准曲线。最后，我们将篮式钳式流量传感器应用于动物实验，成功地检测到了大鼠呼吸道的呼吸特性。
We previously proposed a basket-forceps-type flow sensor, in which a flexible thermal flow sensor is mounted onto basket forceps to fix the flow sensor onto the inside surface of the airway. The basket-forceps-type flow sensor has an asymmetrical structure to prevent reciprocating airflow; thus, we investigated the characteristics of the basket-forceps-type flow sensor under both expired- and inspired-airflow conditions in this study. The thermal flow sensor was fabricated on a flexible polyimide film and mounted onto a guide tube of a basket-forceps. Two heaters and their electrical wiring patterns were designed to produce symmetric heat distribution over the heaters. The effects of the basket structure and guide tube on flow-rate measurement were experimentally evaluated, and it was confirmed that they did not affect sensor output. Conversely, sensor output decreased with the increase in tube diameter due to the reduction in the average flow velocity with the diameter increase. Thus, we carried out a procedure to construct a calibration curve under an arbitrary tube diameter. Finally, we applied the basket-forceps-type flow sensor in an animal experiment in which it successfully detected the breathing properties in the airway of a rat.