Malignant lesions of the liver with high signal intensity on T1‐Weighted MR images
Malignant lesions of the liver with high signal intensity on T1‐Weighted MR images
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T1 加权 MR 图像上具有高信号强度的肝脏恶性病变
DOI：
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发表时间：
1996
影响因子：
4.4
通讯作者：
J. Woosley
中科院分区：
文献类型：
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作者：
N. Kelekis;R. Semelka;J. Woosley
我们的目的是识别 T1 加权图像上具有高信号强度 (SI) 的恶性肝脏病变的组织学类型，并描述 MR 成像特征。使用 1.5-T MR 成像仪对 13 名在 T1 加权图像上具有高 SI 的恶性肝脏病变患者进行研究，使用预对比和连续对比后破坏梯度回波 (SGE) 序列（所有患者）、T2 加权脂肪抑制自旋回波序列（所有患者）、对比前 T1 加权脂肪抑制自旋回波序列（针对 5 名患者的 5 项研究）和对比前异相序列SGE 序列（针对六名患者的七项研究）。回顾性检查图像以确定病变数量；病变大小； T1加权、T2加权和脂肪衰减T1加权图像上病变的SI； T1 加权图像上病灶中高 SI 的分布；和肿瘤强化模式。 7 名患者在 T1 加权图像上患有多个 SI 高的肿瘤，6 名患者患有孤立性肿瘤。 72个病灶直径小于1.5 cm，35个病灶直径大于1.5 cm。 9 名患者为实性恶性病变，4 名患者为囊性恶性病变。所有直径超过 1.5 cm 的肿瘤在 T1 加权图像上 SI 均不均匀，所有小于 1.5 cm 的肿瘤完全均质或均质，有一个小的中央低信号病灶。除了一种含脂肪的肝细胞癌 (HCC) 外，所有肿瘤在 T1 加权脂肪衰减图像上（无论是在激励损坏的脂肪抑制自旋回波上还是在异相 SGE 图像上）都更加明显。在一名患有黑色素瘤转移的患者和一名患有多发性骨髓瘤结节的患者中，在异相 SGE 图像上检测到了明显更多的病灶。高信号的原因被认为是脂肪、黑色素、中心出血或高蛋白质含量，所有这些都可能出现在多种肿瘤中。脂肪衰减技术有助于检测这些病变。
Our purpose was to identify the histologic types of malignant liver lesions with high signal intensity (SI) on T1‐weighted images and to describe the MR imaging features. Thirteen patients with malignant liver lesions high in SI on T1‐weighted images were studied with a 1.5‐T MR imager using pre‐ and serial postcontrast spoiled gradient‐echo (SGE) sequences (all patients), T2‐weighted fat‐suppressed spin‐echo sequences (all patients), precontrast T1‐weighted fat‐suppressed spin‐echo sequences (five studies in five patients), and precontrast out‐of‐phase SGE sequences (seven studies in six patients). Images were reviewed retrospectively to determine number of lesions; lesion size; SI of lesions on T1‐weighted, T2‐weighted, and fat‐attenuated T1‐weighted images; distribution of high SI in lesions on T1‐weighted images; and tumor enhancement pattern. Seven patients had multiple tumors high in SI on T1‐weighted images and six patients had solitary tumors. Seventy‐two lesions were less than 1.5 cm in diameter and 35 lesions were more than 1.5 cm in diameter. Nine patients had solid malignant lesions and four patients had cystic malignant lesions. All tumors more than 1.5 cm in diameter were heterogeneously high in SI on T1‐weighted images, and all tumors less than 1.5 cm were completely homogeneous or homogeneous with a small central hypointense focus. All tumors were more conspicuous on T1‐weighted fat‐attenuated images, both on excitation spoiled fat‐suppressed spin‐echo or on out‐of‐phase SGE images with the exception of one fat‐containing hepatocellular carcinoma (HCC). In one patient with melanoma metastases and one patient with multiple myeloma nodules, appreciably more lesions were detected on out‐of‐phase SGE images. Causes of hyperintensity were considered to be either fat, melanin, central hemorrhage, or high protein content, all of which may be seen in a variety of tumors. Fat‐attenuation techniques are helpful in the detection of these lesions.