Burton's Agammaglobulinemia and COVID-19.

Burton's Agammaglobulinemia and COVID-19.
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DOI:
10.7759/cureus.11701
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发表时间:
2020-11-25
期刊:
Cureus
影响因子:
--
通讯作者:
Howell D
Howell D
中科院分区:
其他
文献类型:
--
作者:
Hovey JG;Tolbert D;Howell D

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在SARS-CoV-2全球大流行期间,许多患有并发症的患者被认为是发病率和死亡率高的风险;然而,那些免疫缺陷的患者患重病的风险更高。在这篇文章中,我们提出了一个26岁的男性与X-连锁无丙种球蛋白血症的历史谁提出了到医院发热和寒战后,暴露于SARS-CoV-2阳性个人。患者住院时间较长,但接受恢复期血浆治疗后症状迅速改善。该病例强调了严重免疫球蛋白缺乏症患者的临床病程,以及合并无丙种球蛋白血症和COVID-19患者的可能治疗方法。
During the SARS-CoV-2 global pandemic, many patients who have co-morbid conditions are considered high risk for morbidity and mortality; however, those who are immunodeficient are at higher risk of becoming seriously ill. In this article, we present a 26-year old male with a history of X-linked agammaglobulinemia who presented to the hospital with fever and chills after exposure to a SARS-CoV-2 positive individual. The patient had a prolonged course in the hospital, but his symptoms improved quickly after receiving convalescent plasma. This case highlights the clinical course of a patient with severe immunoglobulin deficiency and a possible treatment approach for patients with concomitant agammaglobulinemia and COVID-19.
DOI: 10.1016/0092-8674(93)90667-f
发表时间: 1993-01-29
期刊: CELL
影响因子: 64.5
作者:
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