Natural History of Intrameniscal Signal Intensity on Knee MR Images: Six Years of Data from the Osteoarthritis Initiative

Natural History of Intrameniscal Signal Intensity on Knee MR Images: Six Years of Data from the Osteoarthritis Initiative
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DOI:
10.1148/radiol.2015142905
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发表时间:
2016-01-01
期刊:
影响因子:
19.7
通讯作者:
Englund, Martin
Englund, Martin
中科院分区:
医学1区
文献类型:
--
作者:
Kumm, Jaanika;Roemer, Frank W.;Englund, Martin

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目的:为了评估的自然历史的intraperecal信号强度的磁共振(MR)图像的medial compartment.Materials和方法:两个膝盖的269名参与者(55%的妇女,年龄45-55岁)在骨关节炎倡议没有放射性膝关节炎(OA),没有内侧膝关节撕裂在基线进行了研究。一位放射科医生评估了基线和24、48和72个月随访时的3-T MR图像的颅内信号强度和撕裂。一个互补的对数-对数模型与随机效应被用来评估内侧髁撕裂的风险,调整年龄,性别,体重指数,和膝side.Results:在基线,线性intraocular信号强度在内侧间室存在于140膝(26%)。一旦出现,仅在单膝关节中观察到退化。在31个膝关节(19%)中,在前三个时间点的任何一个时间点上,线性内信号强度,信号强度进展为同一节段的撕裂,在单个膝关节中,撕裂发生在相邻节段。相应数量的撕裂,而没有事先发现的神经内信号强度是11(3%)。在调整后的模型中,与无线性信号强度时相比,如果存在线性脑内信号强度,则发生内侧半月板撕裂的风险比为18.2(95%置信区间:8.3,39.8)。只有一个43个膝盖受伤的报道与事件tear.Conclusion:在中年人没有OA,线性intrajuncal信号强度的MR图像是非常不可能解决,应被视为一个危险因素,内侧退行性juncal撕裂。(C)RSNA,2015年
Purpose: To assess the natural history of intrameniscal signal intensity on magnetic resonance (MR) images of the medial compartment.Materials and Methods: Both knees of 269 participants (55% women, aged 45-55 years) in the Osteoarthritis Initiative without radiographic knee osteoarthritis (OA) and without medial meniscal tear at baseline were studied. One radiologist assessed 3-T MR images from baseline and 24-, 48-, and 72-month follow-up for intrameniscal signal intensity and tears. A complementary log-log model with random effect was used to evaluate the risk of medial meniscal tear, adjusting for age, sex, body mass index, and knee side.Results: At baseline, linear intrameniscal signal intensity in the medial compartment was present in 140 knees (26%). Once present, regression only in a single knee was observed. In 31 knees (19%) with linear intrameniscal signal intensity at any of the first three time points, the signal intensity progressed to a tear in the same segment, and in a single knee, the tear occurred in an adjacent segment. The corresponding number of tears without prior finding of intrameniscal signal intensities was 11 (3%). In the adjusted model, the hazard ratio for developing medial meniscal tear was 18.2 (95% confidence interval: 8.3, 39.8) if linear intrameniscal signal intensity was present, compared when there was no linear signal intensity. There was only one of 43 knees with injury reported in conjunction with the incident tear.Conclusion: In middle-aged persons without OA, linear intrameniscal signal intensity on MR images is highly unlikely to resolve and should be considered a risk factor for medial degenerative meniscal tear. (C) RSNA, 2015