Why Do Children With ADHD Discontinue Their Medication?
Why Do Children With ADHD Discontinue Their Medication?
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DOI：
10.1177/0009922812446744
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发表时间：
2012-08-01
影响因子：
1.6
通讯作者：
Finkelstein, Jonathan A.
中科院分区：
文献类型：
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作者：
Toomey, Sara L.;Sox, Colin M.;Finkelstein, Jonathan A.
Objective.研究与父母报告的注意缺陷多动障碍（ADHD）药物停药相关的因素。方法.作者对6至18岁儿童的父母进行了电话调查，这些儿童最近根据保险索赔开始了ADHD药物治疗。结果共有127名最近开始使用ADHD药物的ADHD儿童的父母完成了调查（43%的应答率）; 21%的人停止了ADHD药物治疗。停药者的父母不太可能报告与初级保健提供者讨论ADHD药物的风险和益处（59% vs 82%，P = .03），更可能报告心理副作用（58% vs 21%，P > .001）。多变量分析表明，心理副作用和认为药物疗效不足与停药有关。结论.许多儿童在第一年内停止ADHD药物治疗，通常是因为心理副作用或认为药物有效性不足。需要改进心理副作用管理，设定现实的药物治疗目标和评估治疗成功的方法。
Objective. To examine factors associated with parent-reported discontinuation of attention-deficit/hyperactivity disorder (ADHD) medication. Methods. The authors conducted a telephone survey of parents of children 6 to 18 years old who had recently initiated ADHD medication according to insurance claims. Results. A total of 127 parents of children with ADHD who had recently initiated ADHD medication completed the survey (43% response rate); 21% discontinued the ADHD medication. Parents of discontinuers were less likely to report having discussed the risks and benefits of ADHD medication with primary care providers (59% vs 82%, P = .03) and were more likely to report psychological side effects (58% vs 21%, P > .001). Multivariate analyses demonstrated that both psychological side effects and perceived inadequate medication effectiveness were associated with discontinuation. Conclusions. Many children discontinue ADHD medication within the first year, often because of psychological side effects or perceived inadequate medication effectiveness. Improved methods for psychological side effect management, setting realistic medication goals, and assessing therapeutic success are needed.