Evaluation of an ultrasensitive p24 antigen assay as a potential alternative to human immunodeficiency virus type 1 RNA viral load assay in resource-limited settings

Evaluation of an ultrasensitive p24 antigen assay as a potential alternative to human immunodeficiency virus type 1 RNA viral load assay in resource-limited settings
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DOI:
10.1128/jcm.43.1.506-508.2005
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发表时间:
2005-01-01
影响因子:
9.4
通讯作者:
Dondero, TJ
Dondero, TJ
中科院分区:
医学2区
文献类型:
--
作者:
Respess, RA;Cachafeiro, A;Dondero, TJ

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将一种廉价的酶联免疫吸附法——超灵敏p24抗原测定法(Up24)与RNA病毒载量测定法(VL)进行了比较。Up24在病毒载量大于或等于30000时的检测灵敏度为100%,在病毒载量大于或等于30000时的灵敏度为46.4%
An inexpensive enzyme-linked immunosorbent assay method for human immunodeficiency virus type I quantitation, ultrasensitive p24 antigen assay (Up24), was compared with RNA viral load assay (VL). Up24 had 100% sensitivity of detection at a viral load of greater than or equal to30,000, with sensitivity of 46.4% at a viral load of