Continuous and Noninvasive Measurement of Systolic and Diastolic Blood Pressure by One Mathematical Model with the Same Model Parameters and Two Separate Pulse Wave Velocities
Continuous and Noninvasive Measurement of Systolic and Diastolic Blood Pressure by One Mathematical Model with the Same Model Parameters and Two Separate Pulse Wave Velocities
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DOI：
10.1007/s10439-011-0467-2
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发表时间：
2012-04-01
影响因子：
3.8
通讯作者：
Bi, Min
中科院分区：
文献类型：
--
作者：
Chen, Yan;Wen, Changyun;Bi, Min
人们对连续和无创血压（BP）测量非常感兴趣。然而，许多技术都存在机械结构复杂的缺点。本研究采用光电容积描记法（PPG）采集耳、趾动脉搏动，探讨脉搏波传导速度（PWV）测量血压的新方法。我们之前验证并报告了一个BP-PWV数学模型，该模型使用来自没有心血管疾病证据的人类的测量值，但只能确定与舒张压（DBP）相关的PWV。在本文中，我们提出的方法，确定脉冲传输时间（PTT）在低，正常和高收缩压（SBP）的条件。通过对入射波和反射波的PTT进行平均以减小非系统误差，我们得到了适合于估计SBP的PWV。根据先前校准的模型，通过两个单独的PWV估计SBP和DBP。对26名受试者（年龄19 +/-A1和60 +/-A1）进行实验测量，没有心血管疾病的证据。测量误差（平均差= 2.16 mmHg（SBP）和1.49 mmHg（DBP）;标准差= 6.23 mmHg（SBP）和6.51 mmHg（DBP））符合美国医疗器械促进协会的准确度标准。结果证实，SBP和DBP可以通过具有相同模型参数和两个单独PWV的一个数学模型来估计。
There is keen interest in continuous and noninvasive blood pressure (BP) measurement. However, many technologies have a shortcoming of complex mechanical structure. In our study, two arterial pulses are acquired by photoplethysmography (PPG) at ear and toe in order to explore a new method of measuring BP by pulse wave velocity (PWV). We previously validated and reported a BP-PWV mathematical model with measurements from humans with no evidence of cardiovascular disease, but were only able to determine PWV related to diastolic blood pressure (DBP). In this paper, we propose methods of identifying pulse transmit time (PTT) in low, normal and high systolic blood pressure (SBP) conditions. By averaging the PTT's of incident wave and reflected wave for non-systematic error reduction, we obtain a PWV that is suitable for estimating SBP. SBP and DBP are estimated by two separate PWV's based on the previously calibrated models. Experimental measurements are conducted on 26 subjects (age 19 +/- A 1 and 60 +/- A 1) with no evidence of cardiovascular disease. The measurement errors (Mean Deviation = 2.16 mmHg (SBP) and 1.49 mmHg (DBP); Standard Deviation = 6.23 mmHg (SBP) and 6.51 mmHg (DBP)) satisfy the accuracy criteria of Association for the Advancement of Medical Instrumentation. The results verify that SBP and DBP can be estimated by one mathematical model with the same model parameters and two separate PWV's.