First registry report: lung transplantation in Japan

First registry report: lung transplantation in Japan
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DOI:
10.1007/s11748-007-0161-3
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发表时间:
2008-01-01
影响因子:
1.2
通讯作者:
Nagayasu, Takeshi
Nagayasu, Takeshi
中科院分区:
医学4区
文献类型:
--
作者:
Bando, Toru;Date, Hiroshi;Nagayasu, Takeshi

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自1998年以来的9年中,日本共进行了87例肺移植。由于脑死亡供体的短缺,活体肺叶移植占日本肺移植的三分之二。最常见的适应症是原发性肺动脉高压。手术类型和适应症的分布是日本的特征。尽管数量有限,随访时间短,日本受者的生存率高于国际平均水平,肺移植后的生活质量非常好。为了增加可用肺移植物的数量,我们尝试了各种策略,例如积极使用边缘供体,仔细的供体管理,以及开发新的保存解决方案,但脑死亡供体的短缺仍然是一个严重的问题。目前的移植法需要重新考虑。
A total of 87 lung transplants has been performed for the 9 years since 1998 in Japan. Because of the shortage of brain-dead donors, living-donor lobar lung transplantation accounted for two-thirds of lung transplantation in Japan. The most common indication was primary pulmonary hypertension. The distributions of procedure type and indication were characteristic for Japan. Despite the limited number and the short followup period, the survival for Japanese recipients was better than the international average, and the quality of life after lung transplantation was excellent. To increase the number of available pulmonary grafts, we have tried various strategies, such as active use of marginal donors, careful donor management, and development of new preservation solutions, but the shortage of brain-dead donors remains a serious problem. The current transplant laws need to be reconsidered.