Combined effect of motor imagery and peripheral nerve electrical stimulation on the motor cortex
Combined effect of motor imagery and peripheral nerve electrical stimulation on the motor cortex
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DOI：
10.1007/s00221-013-3513-5
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发表时间：
2013-06-01
影响因子：
2
通讯作者：
Sugawara, Kenichi
中科院分区：
文献类型：
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作者：
Saito, Kei;Yamaguchi, Tomofumi;Sugawara, Kenichi
虽然运动想象增强了皮质脊髓束的兴奋性，但在运动想象过程中没有外周传入输入。与此相反，周围神经电刺激（ES）可以诱导外周传入输入，因此，运动想象和ES的组合可以增强皮质脊髓束的兴奋性相比，单独的运动想象。此外，刺激强度的水平也可能与运动想象过程中皮质脊髓束兴奋性的调节有关。在这里，我们评估了运动想象和外周神经ES的组合是否影响皮质脊髓束的兴奋性，并测量了ES强度对运动想象过程中诱导的兴奋性的影响。想象的任务是一个涉及触摸拇指到小指的运动，而ES涉及同时刺激手腕处的尺神经和正中神经。使用两种不同的ES强度，一种高于运动阈值，另一种高于感觉阈值。此外，我们评估是否实际的运动与传入输入引起的ES调制皮质脊髓束的兴奋性以及运动想象。我们发现，运动想象和ES相结合，增强了大鱼际肌肉运动皮层的兴奋性相比，其他条件。此外，我们确定皮质脊髓束的调制与ES强度有关。然而，我们发现，皮质脊髓束的兴奋性引起的实际运动增强周围神经ES感觉阈值以上。
Although motor imagery enhances the excitability of the corticospinal tract, there are no peripheral afferent inputs during motor imagery. In contrast, peripheral nerve electrical stimulation (ES) can induce peripheral afferent inputs; thus, a combination of motor imagery and ES may enhance the excitability of the corticospinal tract compared with motor imagery alone. Moreover, the level of stimulation intensity may also be related to the modulation of the excitability of the corticospinal tract during motor imagery. Here, we evaluated whether a combination of motor imagery and peripheral nerve ES influences the excitability of the corticospinal tract and measured the effect of ES intensity on the excitability induced during motor imagery. The imagined task was a movement that involved touching the thumb to the little finger, whereas ES involved simultaneous stimulation of the ulnar and median nerves at the wrist. Two different ES intensities were used, one above the motor threshold and another above the sensory threshold. Further, we evaluated whether actual movement with afferent input induced by ES modulates the excitability of the corticospinal tract as well as motor imagery. We found that a combination of motor imagery and ES enhanced the excitability of the motor cortex in the thenar muscle compared with the other condition. Furthermore, we established that the modulation of the corticospinal tract was related to ES intensity. However, we found that the excitability of the corticospinal tract induced by actual movement was enhanced by peripheral nerve ES above the sensory threshold.