Human-animal anthrax outbreak in the Luangwa valley of Zambia in 2011
Human-animal anthrax outbreak in the Luangwa valley of Zambia in 2011
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DOI：
10.1258/td.2012.110454
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发表时间：
2012-07-01
期刊：
影响因子：
0.6
通讯作者：
Higashi, Hideaki
中科院分区：
文献类型：
--
作者：
Hang'ombe, Mudenda B.;Mwansa, James C. L.;Higashi, Hideaki
发达国家的炭疽病发病率有所下降，但在发展中国家，炭疽病仍然是一个公共卫生问题，因为发展中国家的社区生活在与野生动物交界的地区。在赞比亚观察到两栖河马炭疽病爆发。在鱼死亡后，报告了疑似人间病例。本研究的目的是分离和确认炭疽芽孢杆菌，并确定抗菌药物的敏感性，为疾病的管理。在采集的标本中，发现29.4%（95%置信区间[CI]，11.4-56.0）来自人类，42.1%（95% CI，21.1-66.0）来自溪蟹，20.0%（95% CI，6.61-44.3）来自土壤的B呈阳性。炭疽病抗菌药物敏感性试验显示，所有分离株被发现是敏感的推荐抗生素。通过病例管理和向社区解释他们应避免接触死于不明原因的动物，实现了疾病控制。
There has been a reduction of incidences of anthrax in the developed countries but it is still a public health problem in the developing countries where communities live in interface areas with wildlife. An outbreak of anthrax in Hippopotamus amphibious was observed in Zambia. Following the death of hippopotamuses, suspected human cases were reported. The objective of this study was to isolate and confirm Bacillus anthracis and to determine the antimicrobial susceptibility for the management of the disease. Of the specimens collected, 29.4% (95% confidence interval [CI], 11.4-56.0) were from humans, 42.1% (95% CI, 21.1-66.0) were from hippopotamuses and 20.0% (95% CI, 6.61-44.3) from the soil were found to be positive were for B. anthracis. An antimicrobial susceptibility test revealed that all the isolates were found to be sensitive to the recommended antibiotics. The disease control was achieved by case management and by explaining to the communities that they should avoid contact with animals that die from unknown causes.