The Tuskegee Legacy Project: history, preliminary scientific findings, and unanticipated societal benefits.
The Tuskegee Legacy Project: history, preliminary scientific findings, and unanticipated societal benefits.
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DOI：
10.1016/s0011-8532(02)00049-6
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发表时间：
2003-01-01
影响因子：
--
通讯作者：
Claudio, Cristina
中科院分区：
文献类型：
--
作者：
Katz, Ralph V;Kegeles, S Stephen;Claudio, Cristina
本文旨在提供一个相对完整的图片如何试点研究-构思和启动NIDCR资助RRCMOH-成熟成一个坚实的调查线在该中心和“腿”成一个完全资助的研究在下一代NIDCR中心的健康差异，研究中心减少口腔健康差异。它强调了这些中心为多中心提供的自然机会。跨学科研究和研究职业管道大学和牙科学校的学生;重点是，在这种情况下，对少数民族学生。然而，这一系列事件表明，这些类型的研究中心必须以远远超过形成其核心的科学成果的方式做出贡献。在这种情况下，国家人权事务委员会在促成两个具有全国意义的事件方面发挥了核心作用-而且是关键的作用，尽管这是意料之外的-即总统就USPHS-Tuskegee梅毒研究中的滥用行为向非裔美国人社区道歉，以及在Tuskegee大学设立国家研究和保健生物伦理学中心。NIH支持的研究中心完全旨在创造一个科学活动的漩涡，远远超出这些中心最初资助的研究的直接科学目标。这条准则是，整体应该大于其最初组成部分的研究或部分的总和。我们认为，国家人权事务委员会确实做到了这一点-甚至将“整体”扩大到包括广泛的社会影响。远远超出了重要的范围，但仅仅是科学成果-所有的概念和适当的职能，科学NIH资助的研究中心。
This article is intended to provide a relatively complete picture of how a pilot study--conceived and initiated within an NIDCR-funded RRCMOH--matured into a solid line of investigation within that center and "with legs" into a fully funded study within the next generation of NIDCR centers on this topic of health disparities, the Centers for Research to Reduce Oral Health Disparities. It highlights the natural opportunity that these centers provide for multicenter. cross-disciplinary research and for research career pipelining for college and dental school students; with a focus, in this case, on minority students. Futhermore, this series of events demonstrates the rich potential that these types of research centers have to contribute in ways that far exceed the scientific outcomes that form their core. In this instance, the NMOHRC played a central--and critical, if unanticipated--role in contributing to two events of national significance, namely the presidential apology to the African American community for the research abuses of the USPHS--Tuskegee syphilis study and the establishment of the National Center for Bioethics in Research and Health Care at Tuskegee University. Research Centers supported by the NIH are fully intended to create a vortex of scientific activity that goes well beyond the direct scientific aims of the studies initially funded within those centers. The maxim is that the whole should be greater than the sum of its initial constituent studies or parts. We believe that NMOHRC did indeed achieve that maxim--even extending "the whole" to include broad societal impact. well beyond the scope of important, but mere, scientific outcomes--all within the concept and appropriate functions of a scientific NIH-funded research center.