Navigable Space and Traversable Edges Differentially Influence Reorientation in Sighted and Blind Mice
Navigable Space and Traversable Edges Differentially Influence Reorientation in Sighted and Blind Mice
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DOI：
10.1177/09567976211055373
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发表时间：
2022-05
影响因子：
8.2
通讯作者：
M. Normandin;Maria C Garza;M. Ramos-Alvarez;J. Julian;Tuoyo Eresanara;Nishanth Punjaala;J. H. Vasquez-J.
中科院分区：
文献类型：
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作者：
M. Normandin;Maria C Garza;M. Ramos-Alvarez;J. Julian;Tuoyo Eresanara;Nishanth Punjaala;J. H. Vasquez-J.
重新定位使导航员在迷路后能够找回方向。迷失方向的人主要是使用布局的几何形状来重新定位自己，即使存在其他信息线索，如地标。然而，动物用来确定几何形状的具体策略尚不清楚。此外，由于视觉允许受试者快速形成对物体和背景的精确表示，因此尚不清楚视觉在几何学的使用中是否具有确定性作用。在这项研究中，我们测试了视力正常和先天失明的小鼠(NS=8-11)，在不同的环境中，全局形状参数被操纵。结果表明，背景-可穿越空间-的导航承受能力促进了对边界的采样，这决定了几何策略在视力正常和失明的小鼠中的有效使用。然而，盲人动物也可以通过广泛巡逻边界来使用3D边缘有效地重新定位自己，即使可穿越的空间不受这些边界的限制。
Reorientation enables navigators to regain their bearings after becoming lost. Disoriented individuals primarily reorient themselves using the geometry of a layout, even when other informative cues, such as landmarks, are present. Yet the specific strategies that animals use to determine geometry are unclear. Moreover, because vision allows subjects to rapidly form precise representations of objects and background, it is unknown whether it has a deterministic role in the use of geometry. In this study, we tested sighted and congenitally blind mice (Ns = 8–11) in various settings in which global shape parameters were manipulated. Results indicated that the navigational affordances of the context—the traversable space—promote sampling of boundaries, which determines the effective use of geometric strategies in both sighted and blind mice. However, blind animals can also effectively reorient themselves using 3D edges by extensively patrolling the borders, even when the traversable space is not limited by these boundaries.