VARIANT OF INTESTINAL METAPLASIA ASSOCIATED WITH GASTRIC-CARCINOMA - HISTOCHEMICAL-STUDY
VARIANT OF INTESTINAL METAPLASIA ASSOCIATED WITH GASTRIC-CARCINOMA - HISTOCHEMICAL-STUDY
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DOI：
10.1111/j.1365-2559.1979.tb02996.x
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发表时间：
1979-01-01
期刊：
影响因子：
6.4
通讯作者：
FILIPE, MI
中科院分区：
文献类型：
--
作者：
JASS, JR;FILIPE, MI
对32例胃癌和35例消化性溃疡的胃切除标本进行了详细的组织学和组织化学检查，以显示肠上皮化生（IM）的分布和分泌的粘蛋白类型。IM的一种变体，广泛累及胃窦和体部，并过度分泌磺粘蛋白，与具有明显细胞外磺粘蛋白分泌的癌相关。这种变异的IM的鉴定可能有助于解释胃活检。
Gastrectomy specimens, including 32 [human] cases of carcinoma and 35 cases of peptic ulcer, were examined in detail histologically and histochemically to show the distribution of intestinal metaplasia (IM) and types of mucin secreted. A variant of IM, with extensive involvement of antrum and body and excessive secretion of sulfomucin, was associated with carcinomas with appreciable extracellular sulfomucin secretion. The identification of such a variant of IM may help in the interpretation of gastric biopsies.