RADIOGRAPHIC PATTERNS AND ASSOCIATIONS OF OSTEOARTHRITIS OF THE KNEE IN PATIENTS REFERRED TO HOSPITAL
RADIOGRAPHIC PATTERNS AND ASSOCIATIONS OF OSTEOARTHRITIS OF THE KNEE IN PATIENTS REFERRED TO HOSPITAL
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DOI：
10.1136/ard.52.7.520
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发表时间：
1993-07-01
影响因子：
27.4
通讯作者：
DOHERTY, M
中科院分区：
文献类型：
--
作者：
LEDINGHAM, J;REGAN, M;DOHERTY, M
目的-调查转诊至医院的患者中膝关节骨关节炎的不同类型和相关性。方法-252名连续患者（161名妇女，91名男子;平均年龄70岁，范围34-91岁），因膝关节骨关节炎转诊至医院接受临床，放射学检查，结果：85%的患者膝关节骨关节炎的影像学改变（明确的狭窄伴或不伴骨关节炎特征）为双侧。在470例受累膝关节中，277例（59%）累及两个间室，28例（6%）累及三个间室。单侧和孤立性内侧胫股骨关节炎在男性中更常见。焦磷酸钙晶体沉积很常见（132例（28%）膝关节滑液识别; 76例（30%）膝关节软骨钙质沉着症），并与残疾、双侧、多间室和重度放射学骨关节炎、明显骨赘、磨损和囊肿相关。多个临床节点（58例（23%）患者）和影像学多关节指间骨关节炎（66例（26%）患者）与不活动性疼痛、残疾、多间室和严重影像学变化的频率较高相关。 弗赖斯节 疾病在男性中占主导地位，但没有表现出其他association.Conclusions-In一组患者提到医院的膝关节骨关节炎通常是双边的，影响一个以上的隔间。严重和多室放射学改变与焦磷酸钙晶体沉积、结节改变和多关节炎有关。 指间骨关节炎
Objectives-To investigate differing patterns and associations of osteoarthritis of the knee in patients referred to hospital.Methods-Two hundred and fifty two consecutive patients (161 women, 91 men; mean age 70 years, range 34-91 years) referred to hospital with osteoarthritis of the knee underwent clinical, radiographic, and synovial fluid screening.Results-Radiographic changes of osteoarthritis of the knee (definite narrowing with or without osteoarthritic features) were bilateral in 85% of patients. Of 470 knees affected, 277 (59%) were affected in two compartments and 28 (6%) in three compartments. Unilateral and isolated medial tibiofemoral osteoarthritis were more common in men. Calcium pyrophosphate crystal deposition was common (synovial fluid identification in 132 (28%) knees; knee chondrocalcinosis in 76 (30%) patients) and associated with disability, bilateral, multicompartmental and severe radiographic osteoarthritis, marked osteophytosis, attrition, and cysts. Multiple clinical nodes (58 (23%) patients) and radiographic polyarticular interphalangeal osteoarthritis (66 (26%) patients) were associated with a higher frequency of inactivity pain, disability, multicompartmental and severe radiographic change. Forestier's disease predominated in men but showed no other associations.Conclusions-In a group of patients referred to hospital osteoarthritis of the knee is usually bilateral and affects more than one compartment. Severe and multicompartmental radiographic changes are associated with calcium pyrophosphate crystal deposition, nodal change, and polyarticular interphalangeal osteoarthritis.