Palladium catalyzed alkynylation of aryl halides (Sonogashira reaction) in water
Palladium catalyzed alkynylation of aryl halides (Sonogashira reaction) in water
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DOI：
10.1016/j.tetlet.2004.09.131
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发表时间：
2004-11-15
影响因子：
1.8
通讯作者：
Sengupta, S
中科院分区：
文献类型：
--
作者：
Bhattacharya, S;Sengupta, S
在无任何添加剂和相转移催化剂的情况下，在纯水条件下实现了钯催化芳卤烷酰化反应（Sonogashira反应）。该反应只需要0.5 mol%的Pd(PPh3)(4)催化剂，反应速度快（70℃下30分钟），产率高。(C) 2004 Elsevier Ltd.版权所有。
The palladium catalyzed alkynylation of aryl halides (Sonogashira reaction) has been achieved in pure water without any additives or phase transfer catalysts. The reaction, which requires only 0.5 mol% of Pd(PPh3)(4) catalyst, is remarkably fast (30 min at 70degreesC) producing high yields of the aryl alkyne products. (C) 2004 Elsevier Ltd. All rights reserved.