Theoretical and Experimental Approaches to Generalized Autoimmunity

Theoretical and Experimental Approaches to Generalized Autoimmunity
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DOI:
10.1111/j.1600-065x.1990.tb00815.x
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发表时间:
1990-12
影响因子:
8.7
通讯作者:
A. Steinberg;A. Krieg;M. Gourley;D. Klinman
A. Steinberg;A. Krieg;M. Gourley;D. Klinman
中科院分区:
医学1区
文献类型:
--
作者:
A. Steinberg;A. Krieg;M. Gourley;D. Klinman

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This paper summarizes some of our views on the pathogenesis of systemic lupus. It considers theoretical aspects of generalized autoimmunity and data from studies of human and, especially, murine lupus. We emphasize aspects of pathogenesis of disease rather than mechanisms of organ inflammation. In this endeavor, we draw upon both published and unpublished work from our group. We make no attempt to exhaustively cite the literature for the many fields of immunology mentioned.