Respiratory health, effects of ambient air pollution and its modification by air humidity in Drobeta-Turnu Severin, Romania
Respiratory health, effects of ambient air pollution and its modification by air humidity in Drobeta-Turnu Severin, Romania
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DOI：
10.1016/j.scitotenv.2009.02.042
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发表时间：
2009-06-15
影响因子：
9.8
通讯作者：
Schlink, Uwe
中科院分区：
文献类型：
--
作者：
Leitte, Arne Marian;Petrescu, Cristina;Schlink, Uwe
背景：西欧和北美主要报道了环境空气污染与呼吸健康之间的关系。目的：我们的目标是调查罗马尼亚中东欧城市德罗贝塔-图努塞韦林人口之间的这种联系，并量化空气湿度对这种联系的影响。方法：我们调查了慢性阻塞性肺疾病(COPD)、哮喘和慢性支气管炎(CB)与总悬浮颗粒物(TSP)、二氧化硫(SO2)和二氧化氮(NO2)的关系。应用控制时间模式和天气影响的广义加性模型(GAM)。结果：在延迟1天和4天的慢性支气管炎患者中，TSP每增加10µg/m(3)，入院率分别增加3.3%(95%CI：0.3%~6.4%)和2.8%(95%CI：0.1%~5.7%)。湿度越高，TSP对慢性支气管炎的不良影响越小。二氧化硫浓度每增加10微克/立方米，慢性支气管炎住院人数增加6%(95%可信区间：7%-25%)，并有两天的滞后。我们还不能确定一个阈值，低于这个阈值，环境中的TSP和SO2浓度对慢性支气管炎的住院没有影响。我们发现TSP对环境有不良影响，但并不显著。SO2和NO2对呼吸系统住院总人数、COPD和哮喘以及慢性支气管炎的NO2的影响。结论：在慢性支气管炎中，Severin CB与TSP有关，主要是SO2干燥空气加重了TSP的不良反应。(C)2009爱思唯尔B.V.保留所有权利。
Background: Associations between ambient air pollution and respiratory health have been mainly reported for Western Europe and Northern America.Objectives: Our goal was to investigate such associations among the population of Drobeta-Turnu Severin, Romania, a city in Central Eastern Europe (CEE), and to quantify their modification by air humidity. The latter is of increased interest for the current discussion about the potential effects of climate change on human health.Methods: We investigated (study period: 23.01.2001-31.08.2002) the associations between chronic obstructive pulmonary disease (COPD), asthma and chronic bronchitis (CB) and total suspended particles (TSP), sulphur dioxide (SO2) and nitrogen dioxide (NO2). Generalized additive models (GAM) controlling for time patterns and weather effects were applied. Delayed effects up to seven days were analysed in single lag and polynomial distributed lag models (PDLMs).Results: An increase of 10 mu g/m(3) TSP was related to a 3.3% (95% CI: 0.3%-6.4%) and a 2.8% (95% CI: 0.1 %-5.7%) increase for hospital admissions for chronic bronchitis with a lag of one and four days, respectively. The adverse effect of TSP on chronic bronchitis was reduced by higher humidity. An increase of 10 mu g/m(3) SO2 was related to a 6% (95% CI: 7%-25%) increase, with a two days lag, for hospital admissions for chronic bronchitis. We have not been able to identify a threshold, below which ambient TSP and SO2 concentrations have no effect on hospital admissions for chronic bronchitis. We found adverse but nonsignificant influences of TSP. SO2 and NO2 on total respiratory hospital admissions, COPD and asthma and NO2 on chronic bronchitis.Conclusions: We conclude that in Drobeta-Turnu Severin CB is associated with TSP and mainly SO2 Dry air aggravates the adverse effect of TSP. (C) 2009 Elsevier B.V. All rights reserved.