Gender differences in sleep, fatigue, and daytime activity in a pediatric oncology sample receiving dexamethasone.
Gender differences in sleep, fatigue, and daytime activity in a pediatric oncology sample receiving dexamethasone.
复制标题
接受地塞米松的儿科肿瘤样本中睡眠、疲劳和日间活动的性别差异。
DOI：
10.1093/jpepsy/jsm110
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发表时间：
2008
影响因子：
3.6
通讯作者：
Hinds,PamelaS
中科院分区：
文献类型：
--
作者：
Sanford,StacyD;Okuma,JamesO;Pan,Jianmin;Srivastava,DeoKumar;West,Nancy;Farr,Lynne;Hinds,PamelaS
ObjectiveTo examine gender differences in sleep, fatigue, and daytime activity in a sample of children with acute lymphoblastic leukemia (ALL).MethodsParticipants included 88 children in maintenance treatment for ALL (34 girls; 54 boys). Participants wore an actigraph for 10 consecutive days (5 days pre-dexamethasone and 5 days during dexamethasone administration). Fatigue instruments were also administered.ResultsGirls napped more and had less fragmented night sleep than boys did. Wake time after sleep onset was sensitive to dexamethasone administration, revealing a differential direction of response for girls and boys. No gender differences were observed for subjective fatigue or daytime activity in the total sample.ConclusionsOur preliminary findings support gender differences in the sleep of children with cancer after controlling for differences in age, treatment, and risk group. Future research that focuses on the etiology of gender differences and developing interventions will help clarify the clinical application of our findings.
