Citizen science lures gamers into Sweden's Human Protein Atlas

Citizen science lures gamers into Sweden's Human Protein Atlas
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公民科学吸引玩家进入瑞典的人类蛋白质图谱

DOI:
10.1038/nbt0516-452c
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发表时间:
2016
影响因子:
46.9
通讯作者:
M. Peplow
M. Peplow
中科院分区:
工程技术1区
文献类型:
--
作者:
M. Peplow

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《自然生物技术》第34卷,第453期,2016年5月5日,包括世界上第一个致力于众包癌症研究的移动的游戏。“这并不适合所有的事情,”她警告说。“但是,我们越是将科学家与游戏和技术领域的人们聚集在一起,他们就越能够确定我们真正可以开发项目的地方,以全新的方式加速研究。”SciStarter是一家将志愿者与公民科学项目联系起来的非营利组织,其创始人达琳·卡瓦利埃说,克服科学家的怀疑态度是该领域最大的成功之一。她说:“我花在捍卫公民科学上的时间比以往任何时候都少。”SciStarter拥有一个可搜索的数据库,其中包含大约1,400个公民科学项目,沿着培训贡献者的工具,Cavalier说,健康和医学是近年来增长最快的主题之一。与此同时,美国政府在2015年9月发布了一个工具包,使研究人员能够利用现成的公民科学平台,如Zooniverse或CitSci。org而不是从头开始构建它们。“你不必成为开发基于人群的方法的先驱,就可以拥有自己的公民科学项目;你甚至不需要成为程序员,”弗吉尼亚州费尔法克斯人类计算研究所所长Pietro Michelucci说。这些资源,沿着像MMOS这样的组织,意味着“现在开始一个项目比几年前容易得多,”罗宾逊说。她还热衷于让EyeWire更具“游戏性”,并刚刚获得了美国国立卫生研究院的资助,用于生产智能手机版本。到目前为止,制药和生物技术行业还没有接受众包分析,可能是出于对知识产权的担忧。但他们有兴趣利用公民科学热潮来收集数据。雷诺兹说:“制药公司对这一领域非常感兴趣。”例如,PatientsLikeMe是一家总部位于马萨诸塞州的初创公司,允许患者提交有关其健康状况的详细信息,包括症状以及他们认为有效的疗法。它的35万用户可以查看其他人的经验,以指导自己的治疗。
NATURE BIOTECHNOLOGY VOLUME 34 NUMBER 5 MAY 2016 453 including the world’s first mobile game dedicated to crowdsourcing cancer research.“It isn’t appropriate for everything,” she cautions.“But the more we bring scientists together with people in gaming and technology, the more they’ll be able to identify the places where we really can develop projects that accelerate research in an entirely new way.” Overcoming scientists’ skepticism has been one of the field’s biggest successes, says Darlene Cavalier, founder of SciStarter, a nonprofit that connects volunteers to citizen science projects.“I spend far less time defending citizen science than ever before,” she says. SciStarter has a searchable database of about 1,400 citizen science projects, along with tools for training contributors, and Cavalier says that health and medicine has been one of the fastest growing themes in recent years. Meanwhile, the US government released a toolkit in September 2015 to enable researchers to tap into ready-made citizen science platforms such as Zooniverse or CitSci. org rather than building them from scratch.“You don’t have to be a pioneer in developing crowd-based methods to have your own citizen science project; you don’t even need to be a programmer,” says Pietro Michelucci, director of the Human Computation Institute in Fairfax, Virginia. These resources, along with organizations like MMOS, mean that “it’sa lot easier to start a project now than it was a couple of years ago,” says Robinson. She is also keen to make EyeWire more ‘gamey’, and has just won a grant from the US National Institutes of Health to produce a smartphone version.So far, the pharmaceutical and biotech industries have not embraced crowdsourced analysis, perhaps due to concerns over intellectual property. But they are interested in tapping into the citizen science boom to gather data.“Pharma companies are really, really interested in this area,” says Reynolds. PatientsLikeMe, for example, is a Massachusetts-based startup that allows patients to submit details about their health conditions, including symptoms and which therapies they find effective. Its 350,000 users can then look at others’ experiences to guide their own treatment.