Imaging of a linear diode bar for an optical cell stretcher
Imaging of a linear diode bar for an optical cell stretcher
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DOI：
10.1364/boe.6.000807
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发表时间：
2015-01-01
影响因子：
3.4
通讯作者：
Marr, D. W. M.
中科院分区：
文献类型：
--
作者：
Roth, K. B.;Neeves, K. B.;Marr, D. W. M.
我们提出了一种对线性二极管棒激光器进行成像的简化方法，以用作微流体几何结构中的光学展宽器。我们最近表明，这些线性源可用于测量细胞机械特性；然而，源几何形状带来了成像挑战。为了最大限度地减少强度损失并简化微流体系统内的实施，而不使用昂贵的物镜，我们结合非球面和柱面透镜在担架焦平面处创建源的 1:1 图像，并通过测量人类红细胞和中性粒细胞的变形来证明有效性。 (C) 2015年美国光学学会
We present a simplified approach for imaging a linear diode bar laser for application as an optical stretcher within a microfluidic geometry. We have recently shown that these linear sources can be used to measure cell mechanical properties; however, the source geometry creates imaging challenges. To minimize intensity losses and simplify implementation within microfluidic systems without the use of expensive objectives, we combine aspheric and cylindrical lenses to create a 1:1 image of the source at the stretcher focal plane and demonstrate effectiveness by measuring the deformation of human red blood cells and neutrophils. (C) 2015 Optical Society of America