Anemia in old age is associated with increased mortality and hospitalization
Anemia in old age is associated with increased mortality and hospitalization
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DOI：
10.1093/gerona/61.5.474
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发表时间：
2006-05-01
影响因子：
5.1
通讯作者：
Guralnik, Jack M.
中科院分区：
文献类型：
--
作者：
Penninx, Brenda W. J. H.;Pahor, Marco;Guralnik, Jack M.
背景贫血在老年人中很常见，并已被证明会影响老年人的身体机能。为了更全面地了解贫血对健康的不利影响，我们在一个大型的以社区为基础的老年人样本中研究了贫血与死亡和住院结局的关系。数据来自3607名年龄在71岁或以上的人，参加了国家老龄化研究所（NIA）赞助的老年人表皮病研究（EPESE）研究的既定人群。根据世界卫生组织（WHO）标准，贫血定义为女性血红蛋白浓度低于12 g/dL，男性低于13 g/dL。随后的死亡率和住院超过4年的数据来自死亡记录和医疗保险数据库。3607名参与者中有451名（12.5%）存在贫血。在随访期间，贫血患者比非贫血患者更容易死亡（37.0%比22.1%，p
Background. Anemia is common in old age and has been shown to affect older persons' physical function. To more fully understand the detrimental health effects of anemia, we examined the relationship of anemia with death and hospitalization outcomes in a large community-based sample of older persons.Methods. Data are from 3607 persons, aged 71 years or older, participating in the National Institute on Aging (NIA)sponsored Established Populations for Epidermologic Studies of the Elderly (EPESE) study. Anemia was defined according to World Health Organization (WHO) criteria as a hemoglobin concentration below 12 g/dL in women and below 13 g/dL in men. Data on subsequent mortality and hospital admissions over 4 years were obtained from death records and the Medicare database.Results. Anemia was present in 451 of the 3607 (12.5%) participants. During the follow-up period, anemic persons were more likely to die than were nonanemic persons (37.0% vs 22.1%, p