Mapping supramedullary pathways involved in cough using functional brain imaging: Comparison with pain
Mapping supramedullary pathways involved in cough using functional brain imaging: Comparison with pain
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DOI：
10.1016/j.pupt.2008.08.003
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发表时间：
2009-04-01
影响因子：
3.2
通讯作者：
Farrell, Michael J.
中科院分区：
文献类型：
--
作者：
Mazzone, Stuart B.;McGovern, Alice E.;Farrell, Michael J.
一些迹象表明，延髓上脑区从呼吸道接收感觉信息，并为控制咳嗽的脑干神经元提供运动控制。然而，该电路的组织没有任何详细描述。在这篇简短的综述中，我们将讨论在人类和动物身上最先进的脑功能成像技术如何使人们能够前所未有地深入了解有助于控制咳嗽的髓上脑区域。此外，我们还将描述咳嗽相关的高级大脑网络与其他令人厌恶的感觉方式(如疼痛)的处理过程之间的相似之处。(C)2008爱思唯尔有限公司。保留所有权利。
Several indications suggest that supramedullary brain regions receive sensory information from the airways and provide motor control to the brainstem neurons that control coughing. However, the organization of this circuitry has not been described in any detail. In this short review we will discuss how state-of-the-art functional brain imaging techniques in humans and animals will enable unprecedented insights into the supramedullary brain regions that help control coughing. In addition we will describe the likely similarities between cough-related higher brain networks and those involved in the processing of other aversive sensory modalities, such as pain. (c) 2008 Elsevier Ltd. All rights reserved.