123I-IMP brain SPECT imaging in a patient with the interval form of CO poisoning.
123I-IMP brain SPECT imaging in a patient with the interval form of CO poisoning.
复制标题
间歇性一氧化碳中毒患者的 123I-IMP 脑部 SPECT 成像。
DOI：
10.1159/000116665
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发表时间：
1991
影响因子：
2.4
通讯作者：
N. Yamaguchi
中科院分区：
文献类型：
--
作者：
I. Jibiki;K. Kurokawa;N. Yamaguchi
对1例68岁男性间歇性一氧化碳中毒患者进行了N-异丙基-[123I]-对碘苯丙胺(123I-IMP)单光子发射计算机断层扫描(SPECT)脑显像。在大约18天的间隔时间后，在静止-沉默状态下的初始SPECT显示弥漫性区域的高级别低灌注区，延伸到大脑皮层的灰质和白质。急性中毒后328天进行第二次SPECT检查，显示弥漫性低灌注区图像变浅，但在一定程度上与静止性沉默状态的恢复延迟一致。讨论了SPECT脑成像在确定CO中毒的诊断或预后方面的高价值，并与X线或磁共振成像结果进行了比较。
N-isopropyl-[123I]-p-iodoamphetamine (123I-IMP) single-photon emission computed tomography (SPECT) brain imaging was repeatedly performed in a 68-year-old man with the interval form of CO poisoning. The initial SPECT under an akinetic-mutism state following the interval period of about 18 days showed high-grade hypoperfusion images in diffuse regions extending to both the gray and white matter in the cerebral cortex. The second SPECT examination performed 328 days after the acute poisoning showed that the diffuse hypoperfusion images had become lighter but remained to a degree consistent with the delay in the recovery from the akinetic-mutism state. The high utility of SPECT brain imaging in determining the diagnosis or prognosis of CO poisoning was discussed in comparison with X-ray or magnetic-resonance imaging findings.